방선균 분리주 No. 2511-5로부터 포스포리파제 C 저해물질 스코파훈진의 분리

MT 2511-5 was purified as a inhibitor of phospholipase C(PLC) from culture broth of a Streptmyces sp. NO. 2511-5. It was identified as scopafungin, 36-membered marcrolide by physico-chemical and spectroscopic data. Its $IC_{50}$ was 30.mu.M against phospholipase C and it also showed inhibitory activ...

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Veröffentlicht in:	Yaghag-hoi-ji 1995-10, Vol.39 (5), p.554-559
Hauptverfasser:	오원근(Won Keun Oh), 이현선(Hyun Sun Lee), 안순철(Soon Cheol Ahn), 김보연(Bo Yeon Kim), 박문수(Moon Su Park), 민태익(Tae Ick Mheen), 안종석(Jong Seog Ahn)
Format:	Artikel
Sprache:	kor
Online-Zugang:	Volltext
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Zusammenfassung:	MT 2511-5 was purified as a inhibitor of phospholipase C(PLC) from culture broth of a Streptmyces sp. NO. 2511-5. It was identified as scopafungin, 36-membered marcrolide by physico-chemical and spectroscopic data. Its $IC_{50}$ was 30.mu.M against phospholipase C and it also showed inhibitory activity against some fungi.
ISSN:	0377-9556 2383-9457