배초향 지하부의 Diterpene 성분과 그 세포독성

A new diterpene, agastanol[1] with dehydroagastol[2] was isolated from th root of Agastache rugosa, and their structures were elucidated by chemical and instrumental analysis. Agastanol[1], its derivatives, agastanone[3] and methylagastanol[5], and dehydroagastol[2] showed cytotoxic activites agains...

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Veröffentlicht in:생약학회지 1994, Vol.25 (4), p.319-327
Hauptverfasser: 이형규, 변순정, 오세량, 김정일, 김영호, 이정옥, Lee, Hyeong-Kyu, Byon, Soon-Jung, Oh, Se-Ryang, Kim, Jung-Il, Kim, Young-Ho, Lee, Chong-Ock
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Sprache:kor
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Zusammenfassung:A new diterpene, agastanol[1] with dehydroagastol[2] was isolated from th root of Agastache rugosa, and their structures were elucidated by chemical and instrumental analysis. Agastanol[1], its derivatives, agastanone[3] and methylagastanol[5], and dehydroagastol[2] showed cytotoxic activites against in vitro human cancer cell lines. Agastanol[1] showed weak antifungal activity against Trichophyton rubrum.
ISSN:0253-3073