N-치환 5-Hydroxyanthranilic acid의 합성

N-치환 5-Hydroxyanthranilic acid의 합성

Six N-substituted-5-hydroxyanthranilic acids were synthesized by the coupling reaction of 5-tosyloxyanthranilic acid ethyl ester with corresponding acid chlorides. The structure of the obtained compounds was proved by NMR and IR. These compounds did not inhibit the growth of micro-organisms while su...

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Veröffentlicht in:Yaghag-hoi-ji 1993-06, Vol.37 (3), p.243-246
Hauptverfasser: 문정술(Jung Sul Moon), 이강노(Kang Ro Lee), 임중기(Joong Ki Lim), 우원식(Won Sick Woo), 박상우(Sang Woo Park)
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Sprache:kor
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Zusammenfassung:Six N-substituted-5-hydroxyanthranilic acids were synthesized by the coupling reaction of 5-tosyloxyanthranilic acid ethyl ester with corresponding acid chlorides. The structure of the obtained compounds was proved by NMR and IR. These compounds did not inhibit the growth of micro-organisms while suppressed HSV-1 replication in vero cell at 100 $\mu\textrm{g}$/ml.
ISSN:0377-9556
2383-9457