Serum transferrin as Liver fibrosis biomarkerin patients with chronic hepatitis B

Background/Aims: Transferrin and alpha-1 antitrypsin are reportedly associated with liver fibrosis. We evaluated the usefulness of serum transferrin and alpha-1 antitrypsin as new liver fibrosis markers in patients with chronic hepatitis B. Methods: The study included 293 patients with chronic hepat...

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Veröffentlicht in:Clinical and molecular hepatology 2014-12, Vol.20 (4), p.347
Hauptverfasser: Hyo Jung Cho, Soon Sun Kim, Seun Joo Ahn, Joo Han Park, Dong Joon Kim, Young Bae Kim, Sung Won Cho, Jae Youn Cheong
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Zusammenfassung:Background/Aims: Transferrin and alpha-1 antitrypsin are reportedly associated with liver fibrosis. We evaluated the usefulness of serum transferrin and alpha-1 antitrypsin as new liver fibrosis markers in patients with chronic hepatitis B. Methods: The study included 293 patients with chronic hepatitis B who underwent a liver biopsy between October 2005 and June 2009, and who had no history of hepatocellular carcinoma. Serum markers and liver fibrosis stages were compared. Results: Univariate analysis revealed that age (P
ISSN:2287-2728