Continuous Long-Term Entecavir Therapy in Naive Chronic Hepatitis B Patients Showing Partial Virologic Response

Continuous Long-Term Entecavir Therapy in Naive Chronic Hepatitis B Patients Showing Partial Virologic Response

Background/Aims: We investigated the efficacy of continuous long-term entecavir 0.5 mg treatment in naive chronic hepatitis B patients showing a partial virologic response (PVR). Methods: A total of 227 patients were included. PVR was defined as a more than 1 log10 IU/mL decline in detectable serum...

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Veröffentlicht in:Gut and liver 2013-11, Vol.7 (6), p.712
Hauptverfasser: Dae Hun Kwon, In Hee Kim, Bum Su Choung, Dae Seon Ahn, Sun Ho Yoo, Sang Bae Park, Seok Lee, Seong Hun Kim, Sang Wook Kim, Yong Jin Im
Format: Artikel
Sprache:kor
Schlagworte:
Chronic
Entecavir
Hepatitis B
Partial
Response
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Zusammenfassung:Background/Aims: We investigated the efficacy of continuous long-term entecavir 0.5 mg treatment in naive chronic hepatitis B patients showing a partial virologic response (PVR). Methods: A total of 227 patients were included. PVR was defined as a more than 1 log10 IU/mL decline in detectable serum hepatitis B virus (HBV) DNA by polymerase chain reaction (PCR, ≥20 IU/mL) at week 48. A complete virologic response (CVR) was defined as undetectable serum HBV DNA by PCR (
ISSN:1976-2283