신증후군 (腎症候群) 에 병발 (倂發) 된 혈전증 (血栓症)에 관한 (硏究)

Radiologic studies were performed in 20 nephrotics suspected to have thrombosis in renal veins or other sites. The clinical, laboratory and pathologic findings of the patients with thrombosis were analized, and the following results were obtained. 1. Thrombosis was confirmed in 10 of 20 patients studied (50%), among 190 nephrotics admitted (5. 3%) 2. The duration of nephrotic symptoms ranged from 0.5 to 15 months. The clinical and laboratory findings included flank pain, oliguria, fever, leg pain, paraplegia, monoparesis, CVA tenderness, asymme- tric kidneys, acute azotemia, fluctuating proteinuria, renal glycosuria, hematuria, and sterile pyuria, etc. 3. The sites of thrombosis were renalveins or renal and other deep veins in 8, abdominl aorta in one and cerebral artery in the other. 4. The renal pathology showed membranous nephropathy in 5, minimal change lesion in 2, focal segmental glomerular sclerosis in one and diffuse proliferative glomerulonephritis in the other. Throm- bosis was confirmed in 14.3% of nephrotics with membranous nephropathy. 5. 3 patients showed improvement of renal func- tion after anticoagulation therapy.