한국인에서의 IgA 신장병증과 조직적합성 항원과의 관계

한국인에서의 IgA 신장병증과 조직적합성 항원과의 관계

designed to evaluate the pattern of histocompatibility antigens(HLA) and its association with poor prognostic factors in patients with IgAN. Methods : Study population comprised the 69 patients with IgAN which was diagnosed by clinical and pathological findings, and control groups were 202 healthy K...

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Veröffentlicht in:The Korean journal of medicine 1998-02, Vol.54 (2), p.217
Hauptverfasser: 신영신, Young Shin Shin, 김영옥, Young Ok Kim, 박철휘, Chul Whee Park, 윤성노, Sung No Yoon, 양철우, Chul Woo Yang, 김용수, Yong Soo Kim, 장윤식, Yeun Sik Jang, 방병기, Byung Kee Bang, 한훈, Hoon Han
Format: Artikel
Sprache:kor
Schlagworte:
HLA
IgA nephropathy
Korean
poor prognostic factor
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Zusammenfassung:designed to evaluate the pattern of histocompatibility antigens(HLA) and its association with poor prognostic factors in patients with IgAN. Methods : Study population comprised the 69 patients with IgAN which was diagnosed by clinical and pathological findings, and control groups were 202 healthy Korean people. We evaluated the HLA class I serologic typing by standard microlymphocytotoxic technique and the HLA class II genotypes by the two-step polymerase chain reaction. Results : 1. HLA-A was not associated with IgAN. 2. The phenotype frequency of HLA-B55 was 6.1% in patient group and 1.7% in normal control group. HLA- B55 was associated with IRAN(relative risk 3.47, P
ISSN:1738-9364