Helicobactor pylori 의 검출을 위한 Ultrarapid Urease Test 의 유용성에 관한 연구

Objectives: A variety of methods have been developed for the detection of Helicobacter pylori in gastric mucosa. However they have a major disadvantage which is the time required or may be limited by expense. It has been reported that changing the incubation condition permitted ultrarapid diagnosis (ultrarapid urease test). We have examined the diagnostic efficacy of ultrarapid endoscopy room test and compard it with other diagnostic techniques in various gastrointestinal diseases. Methods: 110patients were performed gastroduodenoscopy. Alsco, antral biopsy specimens were taken for ultrarapid endoscopy room test' (1minute and 5minute records), CLO test and histologic test (Hematoxylin & Eosin, Giemsa stain). We have determinde immunoglobulin-G titer for Helicobacter pylori. Results: Using histologic test as the gold standard, ultrarapid urease test produced a sensitivity of 85.7% (1 minute record), 91.4% (5minute record) respectively and a specificity of 92.9% (1minute record), 78.6%(5minute record) respectively. The diagnostic accuracy of the test was 87.8% in 1 minute and 5minute record. Conclusion: Ultrarapid urease test is a rapid, inexpensive, easily available and reliable technique for the detection of Helicobacter pylori in endoscopy room.