갑상선 기능 저하증에 동반된 대퇴골두의 무혈성 괴사 1 예

There has been no report of avascular necrosis of femoral head with hypothyroidism. Avascular necrosis of femoral head develop secondary to femur neck fracture or traumatic dislocation of hip joint But the pathogenesis of idiopathic necrosis of femoral head is not clear as that seen in trauma, Several causes linked to avascular necrosis are as follows: administration of corticosteroid, Diahetes Mellitus, alcohol drinking, sickle cell disease, gout, connective tissue disease, coagulopathy, fat embolism, iron overolad, etc. Recently we experienced a 42-year old woman complained of left hip joint pain. Radiologic finding of left hip joint showed decreased mottled density on left femoral haad. we could not find any etiologic factors described above. Only T3 and T4 were decreased and TSH was increased markedly. We started thyroid hormone replacement. 1 month later after treatment, left hip joint pain was subcided. 6 months later, previous radiologic finding was normalized on follow up study. We can not conclude that hypothyroidism caused avascular necrosis of femoral had, but we infer that hypothyroidism might influence on femoral head lesion at least.