소화성 궤양에 대한 임상적 고찰

Background/Aims : The aim of this study was to investigate whether the epidemiologic patterns of peptic ulcer can be changed by environmental changes. Methods: We studied 1,263 patients with peptic ulcer and the results were compared with those of 8 years age. Results: Of 1,263 cases, patients with gastric ulcer (GU), duodenal ulcer, and combined ulcer (CU) are (44.3%), (41.4%), and (14.3%), respectively. Those in 8 years ago were (41.5%), (51.4%), and (7.1%), respectively. The mean age of the patients with GU, DU, and CU are 52.9, 42.8, and 50.0 years, respectively. Those in 8 years ago were 50.3, 39.6, and 47.3 years, respectively. The mean age of patients with gastric ulcer, duodenal ulcer, and combined ulcer was 52.9±13.0 years vs. 50.3±14 years, 42.8±13.0 years vs. 39.6±12 years, and 50.0±13.0 years vs. 47.9±13 years respectively. The percentage of smokers (GU:86.6%, DU:79.5%) in male with peptic ulcer was higher than 73% in the general population. Conclusions : Comparing this results with the those of eight years ago, we found the increased incidence of gastric ulcer, and the decreased recurrence of peptic ulcer. These differences may be due to the increase of aged population, increased association with NSAIDs, and increased eradication rates of H. pylori. (Kor J Gastroenterol 2000;36:336 - 347)