소간세포암에서의 다발성 골전이 1예

Hepatocellular carcinoma (HCC) usually spreads to the lung and regional lymph nodes by direct extention, lymphatic route, and vascular dissemination. Rarely, it happens to metastasize to the bones. Metastases to other organs such as bones seem to occur by erosions of pulmonary veins into the systemic circulation or retrogradely, into vertebral venous plexuses via portal vein. Treatment results were poor with a median survival of 5 months. We experienced multiple bone metastases in a 61-year-old male patient with small HCC. In conclusion, this report is valuable in presenting unusual multiple bone metastases in small HCC. (Kor J Gastroenterol 2000;35:512 - 516)