위암과 대장암이 병발한 가족성 대장 용종증 1예

Familial adenomatious polyposis (FAP) includes early development of up to thousands of colorectal adenoma and of coloaic adenocarcinoma in all untreated cases. Moreover, a variety of extracolonic manifestation are seen. Several reports have demonstrated a high incidence of gastroduodenal polyps in FAP patient. Fundic gland polypois is found in half of polyposis patient, It is an non-geoplastic condition with hundreds of sessile polyps in the gastric fundus consisting of cystic dilated fundic glands without epithelial dyeplasia, In western countries, gastric adenoma and carcinoma are rare findings in FAP patients. Until present time, only 2 cases in western countries and 8 cases in Japanese series were reported in literature. So it is generally suggested that the development of gastric carcinoma is related not only to racial and environmental factors, but also to a genetic effect, this may be the first case-report in Korea. Here we report the case with familial adenomatous polyposis, presenting with gastric and colonic adenocarcinoma.