간장 ( 肝臟 ) 및 담도 ( 膽道 ) : 만성 간질환에서 SGD - F의 효과

The single blind clinical trials of SGD-F (complex capsule of UDCA 100 mg and vitamin B1 10 mg and B, 10 mg) were carried out in 30 patients with chronic liver disease (and 10 received the placbo) T.I.D. for 4 weeeks. In the SGD-F treated group, subjective symptoms (nausea, anorexia and fatigue) proved to be improved in a statistically significant manner than those of placebo. And the bio- chemical parameters (SGOT & SGPT) were improved significantly in the SGD-F groups. Untoward side effects were not significant and easily controlled by discontinuing the drugs. In conclusion, ursodeoxycholic acid 100 mg with vitamin B1 10 mg and B2 10 mg (t.i.d. for 4 weeks) appears to be effective for reliefing symptoms and safe for the treatment of patients with chronic liver disease.