위장관 ( 胃腸管 ) : 에탄올에 의한 흰쥐의 위점막 손상에서 위점막 항 산화 효소에 대한 D - Methyl Prostaglandin E1 의 영향
To clarify the mechanism of ethanol induced gastric mucosal damage and protective effect of d-methyl prostaglandin (PG) E against the gastric mucosal damage, the activiteis of superoxide (SOD), catalase, glutathione peroxidase of rat stomach were measured after topical application of ethanol in stom...
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| Veröffentlicht in: | The Korean journal of gastroenterology 1990-01, Vol.22 (4), p.776 |
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| container_title | The Korean journal of gastroenterology |
| container_volume | 22 |
| creator | 김종숙 Jong Suk Kim 이일남 Il Nam Lee 임종찬 Jong chan Lim 장세경 Se Kyung Chang 조현덕 Hyon Dug Cho |
| description | To clarify the mechanism of ethanol induced gastric mucosal damage and protective effect of d-methyl prostaglandin (PG) E against the gastric mucosal damage, the activiteis of superoxide (SOD), catalase, glutathione peroxidase of rat stomach were measured after topical application of ethanol in stomach of rats with or woitout d-methyl PGE pretreatment.Variable doses of d-methy1 PGE were given intragastrically at 30mins before the administration of 75% ethanol.The results were summarized as follows;1) The SOD, catalase, glutathion peroxedase activities increase with different concentration of ethanol.2) The each eazyme actinity also shwed dose dependent decrease in the d-methyl PGE pretreatment group than only 75% ethanol application group. According to our experimint it was suggested that superoxide radical may play a role on ehtnol-indeced gastric damage in rats. |
| format | Article |
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According to our experimint it was suggested that superoxide radical may play a role on ehtnol-indeced gastric damage in rats.</description><identifier>ISSN: 1598-9992</identifier><language>kor</language><publisher>대한소화기학회</publisher><ispartof>The Korean journal of gastroenterology, 1990-01, Vol.22 (4), p.776</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>김종숙</creatorcontrib><creatorcontrib>Jong Suk Kim</creatorcontrib><creatorcontrib>이일남</creatorcontrib><creatorcontrib>Il Nam Lee</creatorcontrib><creatorcontrib>임종찬</creatorcontrib><creatorcontrib>Jong chan Lim</creatorcontrib><creatorcontrib>장세경</creatorcontrib><creatorcontrib>Se Kyung Chang</creatorcontrib><creatorcontrib>조현덕</creatorcontrib><creatorcontrib>Hyon Dug Cho</creatorcontrib><title>위장관 ( 胃腸管 ) : 에탄올에 의한 흰쥐의 위점막 손상에서 위점막 항 산화 효소에 대한 D - Methyl Prostaglandin E1 의 영향</title><title>The Korean journal of gastroenterology</title><addtitle>대한소화기학회지</addtitle><description>To clarify the mechanism of ethanol induced gastric mucosal damage and protective effect of d-methyl prostaglandin (PG) E against the gastric mucosal damage, the activiteis of superoxide (SOD), catalase, glutathione peroxidase of rat stomach were measured after topical application of ethanol in stomach of rats with or woitout d-methyl PGE pretreatment.Variable doses of d-methy1 PGE were given intragastrically at 30mins before the administration of 75% ethanol.The results were summarized as follows;1) The SOD, catalase, glutathion peroxedase activities increase with different concentration of ethanol.2) The each eazyme actinity also shwed dose dependent decrease in the d-methyl PGE pretreatment group than only 75% ethanol application group. 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| identifier | ISSN: 1598-9992 |
| ispartof | The Korean journal of gastroenterology, 1990-01, Vol.22 (4), p.776 |
| issn | 1598-9992 |
| language | kor |
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| source | DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
| title | 위장관 ( 胃腸管 ) : 에탄올에 의한 흰쥐의 위점막 손상에서 위점막 항 산화 효소에 대한 D - Methyl Prostaglandin E1 의 영향 |
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