간 , 담도 및 췌장 : 악성 종양과 간경변에 동반된 복수의 Lipid 분석의 의미

To evaluate the difference of ascitic lipids in liver cirrhosis and cancer, the concentrations of phosphosipids, cholesterol triglycerides and total protein were studied in 30 patients with liver cirrhosis, 22 patients with various neoplasms. The ascitic lipids, especially in phospholipids, and total protein were higher in the group with ma1ignant neoplasm (phospholipids: 21.94+-16.2 vs 48.76+-26,08 mg/dl, cholesterol: 19.24+-18.26 vs 50. 33+-36.09 mg/dl, triglycerides: 21.70+-11.76 vs 33.00+-16.50 mg/dl, total protein; 1.04+-0.45 vs 2.70+-1.47 gmjdl). The best discrimination values were 35 mg/dl for phopholipids, 28 mg/dl for cholesterol, 29.5 mg/ dl for triglycerides and 2.O gm/dl for protein. Application of these cut off points revealed on efficiency of 80.4% for phospholipids, 77.5% for cholesterol, 71.8% for triglycerides and 80.8% for protein. We conclude that ascitic lipids offers an excellent diagnostic discrimination between cirrhosis and malignant neoplasms, but further investigations are needed in tuberculosis.