간장 및 담도 : B형 만성 활동성 간염 환자에 있어서의 말초혈액 T , B 및 IgG Fc 수용체 임파구의 동태에 관한 연구

Peripheral blood lymphocytes were estimated in 34 patients with chronic active hepatitis type B and in 22 normal controls, using a battery of surface markers for T cells, B cells and IgG Fc-receptor bearing cells. 1n all groups of patients of CAH with absolute numbers of active E-rosette forming cells as well as total T lymphocytes were decreased. In patients with CAH without cirrhosis, active E-rosette forming cells were increased. In patients with CAH with cirrhosis, absolute numbers of total T lymphocytes were decreased; however, no consistent changes in complement and IgG Fc-receptor bearing lymphocytes were observed. These results suggest the factors which mainly affect T lymphocytes is probably secondary to the liver damage and the importance of monitoring these lymphocyte subpopulations in patients with this disease is emphasized.