Review of Pharmacokinetic, Pharmacodynamic and Clinical Studies with a Modern Combination of Amoxicillin/Sulbactam

Amoxicillin/sulbactam is a modern antimicrobial combination. This combination proved to be useful for the treatment of several infections caused by different microorganisms, mainly with the β-lactamase-producing species. In this review we present the most relevant pharmacokinetic, pharmacodynamic an...

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Veröffentlicht in:	Chemotherapy (Basel) 2006-01, Vol.52 (4), p.200-204
Hauptverfasser:	Soutric, J., Bantar, C., Caruso, N., Heguilén, R., Casellas Jr, J.M., Casellas, J.M., Farinati, A., Jasovich, A., Arenoso, H., Rodriguez, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amoxicillin - pharmacokinetics Amoxicillin - pharmacology Anti-Bacterial Agents - pharmacokinetics Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteria - drug effects Bacteria - isolation & purification Biological and medical sciences Clinical Study Clinical Trials as Topic Drug Therapy, Combination Humans Infections Medical sciences Medical treatment Microbiology Pharmacology Pharmacology. Drug treatments Sulbactam - pharmacokinetics Sulbactam - pharmacology
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Zusammenfassung:	Amoxicillin/sulbactam is a modern antimicrobial combination. This combination proved to be useful for the treatment of several infections caused by different microorganisms, mainly with the β-lactamase-producing species. In this review we present the most relevant pharmacokinetic, pharmacodynamic and clinical information associated with its use.
ISSN:	0009-3157 1421-9794
DOI:	10.1159/000093593