Plaque Fluoride Concentrations Are Dependent on Plaque Calcium Concentrations
Despite the 1,000-fold difference between the fluoride concentrations ([F]) in dentifrices and fluoridated drinking water, clinical and epidemiological studies have shown that they have similar cariostatic effects. This double-blind, crossover study was done to determine whether the [F] in dental pl...
Gespeichert in:
Veröffentlicht in: | Caries research 2002-07, Vol.36 (4), p.256-265 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 265 |
---|---|
container_issue | 4 |
container_start_page | 256 |
container_title | Caries research |
container_volume | 36 |
creator | Whitford, Gary M. Wasdin, John L. Schafer, Tara E. Adair, Steven M. |
description | Despite the 1,000-fold difference between the fluoride concentrations ([F]) in dentifrices and fluoridated drinking water, clinical and epidemiological studies have shown that they have similar cariostatic effects. This double-blind, crossover study was done to determine whether the [F] in dental plaque is related more to the [F] of the dentifrice used or to the plaque concentrations of calcium and magnesium. The subjects (n = 13) were adults and residents of a city served with fluoridated drinking water. After 1 week of using a fluoridated dentifrice (940 ppm) or a placebo dentifrice, whole saliva and plaque were collected 1.0 h and approximately 12 h after the last use of the dentifrices. The average salivary [F] after brushing with the F dentifrice was higher than after using the placebo. The average plaque [F] 1.0 h after brushing with the F dentifrice was higher than after using the placebo (p < 0.01), but the difference at 12 h was not significant. Plaque [Ca] and [F] were directly related under all experimental conditions (p = 0.0001). The relationships between plaque [Mg] and [F] were weaker and inconsistent. Based on these findings and reports in the literature it is concluded that, for persons whose drinking water is fluoridated, plaque [F] throughout much of the day is not significantly increased by the use of a fluoridated dentifrice. Instead they are directly related to plaque [Ca]. These findings offer at least a partial explanation for why fluoridated dentifrices and drinking water have similar cariostatic effects. |
doi_str_mv | 10.1159/000063931 |
format | Article |
fullrecord | <record><control><sourceid>proquest_karge</sourceid><recordid>TN_cdi_karger_primary_63931</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72070023</sourcerecordid><originalsourceid>FETCH-LOGICAL-c394t-4947fb6fe70b457c0b0e81dc3d73c0d31824d5e087579668724c3378243297ce3</originalsourceid><addsrcrecordid>eNpt0M1LwzAYBvAgipvTg2dBigfBQzVfbdrjqJsKE0UUvJU0eSvVtqlJe_C_N7o6Qcwl8OaXl4cHoUOCzwmJ0gvsT8xSRrbQlHBKwlTEz9to6sdJGEdxMkF7zr1iTHgcJ7toQiglCRV8im7va_k-QLCsB2MrDUFmWgVtb2VfmdYFcwvBJXTQaj8MTBuMPpO1qobmD99HO6WsHRyM9ww9LReP2XW4uru6yearULGU9yFPuSiLuASBCx4JhQsMCdGKacEU1sxn4zoCnIhIpD6xoFwxJvyU0VQoYDN0ut7bWePTuD5vKqegrmULZnC5oFhgTJmHZ2uorHHOQpl3tmqk_cgJzr-6yzfdeXs8Lh2KBvSvHMvy4GgN3qR9AbsBP99P_n3NHhbfIO90yT4BToN8bQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72070023</pqid></control><display><type>article</type><title>Plaque Fluoride Concentrations Are Dependent on Plaque Calcium Concentrations</title><source>Karger Journals</source><source>MEDLINE</source><creator>Whitford, Gary M. ; Wasdin, John L. ; Schafer, Tara E. ; Adair, Steven M.</creator><creatorcontrib>Whitford, Gary M. ; Wasdin, John L. ; Schafer, Tara E. ; Adair, Steven M.</creatorcontrib><description>Despite the 1,000-fold difference between the fluoride concentrations ([F]) in dentifrices and fluoridated drinking water, clinical and epidemiological studies have shown that they have similar cariostatic effects. This double-blind, crossover study was done to determine whether the [F] in dental plaque is related more to the [F] of the dentifrice used or to the plaque concentrations of calcium and magnesium. The subjects (n = 13) were adults and residents of a city served with fluoridated drinking water. After 1 week of using a fluoridated dentifrice (940 ppm) or a placebo dentifrice, whole saliva and plaque were collected 1.0 h and approximately 12 h after the last use of the dentifrices. The average salivary [F] after brushing with the F dentifrice was higher than after using the placebo. The average plaque [F] 1.0 h after brushing with the F dentifrice was higher than after using the placebo (p < 0.01), but the difference at 12 h was not significant. Plaque [Ca] and [F] were directly related under all experimental conditions (p = 0.0001). The relationships between plaque [Mg] and [F] were weaker and inconsistent. Based on these findings and reports in the literature it is concluded that, for persons whose drinking water is fluoridated, plaque [F] throughout much of the day is not significantly increased by the use of a fluoridated dentifrice. Instead they are directly related to plaque [Ca]. These findings offer at least a partial explanation for why fluoridated dentifrices and drinking water have similar cariostatic effects.</description><identifier>ISSN: 0008-6568</identifier><identifier>EISSN: 1421-976X</identifier><identifier>DOI: 10.1159/000063931</identifier><identifier>PMID: 12218274</identifier><language>eng</language><publisher>Basel, Switzerland</publisher><subject>Adult ; Analysis of Variance ; Calcium - analysis ; Cariostatic Agents - administration & dosage ; Cariostatic Agents - analysis ; Cross-Over Studies ; Dental Enamel Solubility ; Dental Plaque - chemistry ; Dentifrices - chemistry ; Dentistry ; Double-Blind Method ; Female ; Fluoridation ; Fluorides - administration & dosage ; Fluorides - analysis ; Humans ; Linear Models ; Magnesium - analysis ; Male ; Middle Aged ; Original Paper ; Saliva - chemistry</subject><ispartof>Caries research, 2002-07, Vol.36 (4), p.256-265</ispartof><rights>2002 S. Karger AG, Basel</rights><rights>Copyright 2002 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c394t-4947fb6fe70b457c0b0e81dc3d73c0d31824d5e087579668724c3378243297ce3</citedby><cites>FETCH-LOGICAL-c394t-4947fb6fe70b457c0b0e81dc3d73c0d31824d5e087579668724c3378243297ce3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2423,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12218274$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Whitford, Gary M.</creatorcontrib><creatorcontrib>Wasdin, John L.</creatorcontrib><creatorcontrib>Schafer, Tara E.</creatorcontrib><creatorcontrib>Adair, Steven M.</creatorcontrib><title>Plaque Fluoride Concentrations Are Dependent on Plaque Calcium Concentrations</title><title>Caries research</title><addtitle>Caries Res</addtitle><description>Despite the 1,000-fold difference between the fluoride concentrations ([F]) in dentifrices and fluoridated drinking water, clinical and epidemiological studies have shown that they have similar cariostatic effects. This double-blind, crossover study was done to determine whether the [F] in dental plaque is related more to the [F] of the dentifrice used or to the plaque concentrations of calcium and magnesium. The subjects (n = 13) were adults and residents of a city served with fluoridated drinking water. After 1 week of using a fluoridated dentifrice (940 ppm) or a placebo dentifrice, whole saliva and plaque were collected 1.0 h and approximately 12 h after the last use of the dentifrices. The average salivary [F] after brushing with the F dentifrice was higher than after using the placebo. The average plaque [F] 1.0 h after brushing with the F dentifrice was higher than after using the placebo (p < 0.01), but the difference at 12 h was not significant. Plaque [Ca] and [F] were directly related under all experimental conditions (p = 0.0001). The relationships between plaque [Mg] and [F] were weaker and inconsistent. Based on these findings and reports in the literature it is concluded that, for persons whose drinking water is fluoridated, plaque [F] throughout much of the day is not significantly increased by the use of a fluoridated dentifrice. Instead they are directly related to plaque [Ca]. These findings offer at least a partial explanation for why fluoridated dentifrices and drinking water have similar cariostatic effects.</description><subject>Adult</subject><subject>Analysis of Variance</subject><subject>Calcium - analysis</subject><subject>Cariostatic Agents - administration & dosage</subject><subject>Cariostatic Agents - analysis</subject><subject>Cross-Over Studies</subject><subject>Dental Enamel Solubility</subject><subject>Dental Plaque - chemistry</subject><subject>Dentifrices - chemistry</subject><subject>Dentistry</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Fluoridation</subject><subject>Fluorides - administration & dosage</subject><subject>Fluorides - analysis</subject><subject>Humans</subject><subject>Linear Models</subject><subject>Magnesium - analysis</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Original Paper</subject><subject>Saliva - chemistry</subject><issn>0008-6568</issn><issn>1421-976X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0M1LwzAYBvAgipvTg2dBigfBQzVfbdrjqJsKE0UUvJU0eSvVtqlJe_C_N7o6Qcwl8OaXl4cHoUOCzwmJ0gvsT8xSRrbQlHBKwlTEz9to6sdJGEdxMkF7zr1iTHgcJ7toQiglCRV8im7va_k-QLCsB2MrDUFmWgVtb2VfmdYFcwvBJXTQaj8MTBuMPpO1qobmD99HO6WsHRyM9ww9LReP2XW4uru6yearULGU9yFPuSiLuASBCx4JhQsMCdGKacEU1sxn4zoCnIhIpD6xoFwxJvyU0VQoYDN0ut7bWePTuD5vKqegrmULZnC5oFhgTJmHZ2uorHHOQpl3tmqk_cgJzr-6yzfdeXs8Lh2KBvSvHMvy4GgN3qR9AbsBP99P_n3NHhbfIO90yT4BToN8bQ</recordid><startdate>20020701</startdate><enddate>20020701</enddate><creator>Whitford, Gary M.</creator><creator>Wasdin, John L.</creator><creator>Schafer, Tara E.</creator><creator>Adair, Steven M.</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020701</creationdate><title>Plaque Fluoride Concentrations Are Dependent on Plaque Calcium Concentrations</title><author>Whitford, Gary M. ; Wasdin, John L. ; Schafer, Tara E. ; Adair, Steven M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c394t-4947fb6fe70b457c0b0e81dc3d73c0d31824d5e087579668724c3378243297ce3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Analysis of Variance</topic><topic>Calcium - analysis</topic><topic>Cariostatic Agents - administration & dosage</topic><topic>Cariostatic Agents - analysis</topic><topic>Cross-Over Studies</topic><topic>Dental Enamel Solubility</topic><topic>Dental Plaque - chemistry</topic><topic>Dentifrices - chemistry</topic><topic>Dentistry</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Fluoridation</topic><topic>Fluorides - administration & dosage</topic><topic>Fluorides - analysis</topic><topic>Humans</topic><topic>Linear Models</topic><topic>Magnesium - analysis</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Original Paper</topic><topic>Saliva - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Whitford, Gary M.</creatorcontrib><creatorcontrib>Wasdin, John L.</creatorcontrib><creatorcontrib>Schafer, Tara E.</creatorcontrib><creatorcontrib>Adair, Steven M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Caries research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Whitford, Gary M.</au><au>Wasdin, John L.</au><au>Schafer, Tara E.</au><au>Adair, Steven M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Plaque Fluoride Concentrations Are Dependent on Plaque Calcium Concentrations</atitle><jtitle>Caries research</jtitle><addtitle>Caries Res</addtitle><date>2002-07-01</date><risdate>2002</risdate><volume>36</volume><issue>4</issue><spage>256</spage><epage>265</epage><pages>256-265</pages><issn>0008-6568</issn><eissn>1421-976X</eissn><abstract>Despite the 1,000-fold difference between the fluoride concentrations ([F]) in dentifrices and fluoridated drinking water, clinical and epidemiological studies have shown that they have similar cariostatic effects. This double-blind, crossover study was done to determine whether the [F] in dental plaque is related more to the [F] of the dentifrice used or to the plaque concentrations of calcium and magnesium. The subjects (n = 13) were adults and residents of a city served with fluoridated drinking water. After 1 week of using a fluoridated dentifrice (940 ppm) or a placebo dentifrice, whole saliva and plaque were collected 1.0 h and approximately 12 h after the last use of the dentifrices. The average salivary [F] after brushing with the F dentifrice was higher than after using the placebo. The average plaque [F] 1.0 h after brushing with the F dentifrice was higher than after using the placebo (p < 0.01), but the difference at 12 h was not significant. Plaque [Ca] and [F] were directly related under all experimental conditions (p = 0.0001). The relationships between plaque [Mg] and [F] were weaker and inconsistent. Based on these findings and reports in the literature it is concluded that, for persons whose drinking water is fluoridated, plaque [F] throughout much of the day is not significantly increased by the use of a fluoridated dentifrice. Instead they are directly related to plaque [Ca]. These findings offer at least a partial explanation for why fluoridated dentifrices and drinking water have similar cariostatic effects.</abstract><cop>Basel, Switzerland</cop><pmid>12218274</pmid><doi>10.1159/000063931</doi><tpages>10</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0008-6568 |
ispartof | Caries research, 2002-07, Vol.36 (4), p.256-265 |
issn | 0008-6568 1421-976X |
language | eng |
recordid | cdi_karger_primary_63931 |
source | Karger Journals; MEDLINE |
subjects | Adult Analysis of Variance Calcium - analysis Cariostatic Agents - administration & dosage Cariostatic Agents - analysis Cross-Over Studies Dental Enamel Solubility Dental Plaque - chemistry Dentifrices - chemistry Dentistry Double-Blind Method Female Fluoridation Fluorides - administration & dosage Fluorides - analysis Humans Linear Models Magnesium - analysis Male Middle Aged Original Paper Saliva - chemistry |
title | Plaque Fluoride Concentrations Are Dependent on Plaque Calcium Concentrations |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-17T21%3A06%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_karge&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Plaque%20Fluoride%20Concentrations%20Are%20Dependent%20on%20Plaque%20Calcium%20Concentrations&rft.jtitle=Caries%20research&rft.au=Whitford,%20Gary%20M.&rft.date=2002-07-01&rft.volume=36&rft.issue=4&rft.spage=256&rft.epage=265&rft.pages=256-265&rft.issn=0008-6568&rft.eissn=1421-976X&rft_id=info:doi/10.1159/000063931&rft_dat=%3Cproquest_karge%3E72070023%3C/proquest_karge%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72070023&rft_id=info:pmid/12218274&rfr_iscdi=true |