Assessment of Patients with Intracerebral Hemorrhage or Hemorrhagic Transformation in the VENOST Study
Introduction: Cerebral venous and sinus thrombosis (CVST) may lead to cerebral edema and increased intracranial pressure; besides, ischemic or hemorrhagic lesions may develop. Intracerebral hemorrhages occur in approximately one-third of CVST patients. We assessed and compared the findings of the ce...
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Veröffentlicht in: | European neurology 2020, Vol.83 (6), p.615-621 |
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creator | Duman, Taşkın Yayla, Vildan Uludüz, Derya Özaydın Göksu, Eylem Yürekli, Vedat Ali Genç, Hamit Utku, Uygar Çınar, Nilgün Tekeli, Hakan Sungur, Mehmet Ali Tokuç, Firdevs Ezgi Uzuner, Nevzat Şenol, Mehmet Güney Yılmaz, Arda Gökçe, Mustafa Demirci, Seden Küsbeci, Özge Yılmaz Uzuner, Gülnur Tekgöl Şahin, Şevki Batur Çağlayan, Hale Zeynep Açıkgöz, Mustafa Özdağ, Fatih Baybaş, Sevim Ekmekçi, Hakan Çabalar, Murat Yaman, Mehmet Bektaş, Hesna Kaplan, Yüksel Göksel, Başak Karakurum Milanlıoğlu, Aysel Necioğlu Örken, Dilek Aluçlu, Mehmet Ufuk Çolakoğlu, Sena Tüfekçi, Ahmet Bakar, Mustafa Nazlıel, Bijrn Taşçılar, Nida Göksan, Baki Kozak, Hasan Hüseyin Mısırlı, Handan Küçükoğlu, Hayriye Midi, İpek Mengüllüoğlu, Necdet Aytaç, Emrah Yeşilot, Nilüfer İnce, Birsen Yalın, Osman Özgür Güneş, Taşkın Oruç, Serdar Mayda Domaç, Füsun Öztürk, Şerefnur Karahan, Ali Erdoğan, Hacı Ali Afşar, Nazire |
description | Introduction: Cerebral venous and sinus thrombosis (CVST) may lead to cerebral edema and increased intracranial pressure; besides, ischemic or hemorrhagic lesions may develop. Intracerebral hemorrhages occur in approximately one-third of CVST patients. We assessed and compared the findings of the cerebral hemorrhage (CH) group and the CVST group. Materials and Methods: In the VENOST study, medical records of 1,193 patients with CVST, aged over 18 years, were obtained from 35 national stroke centers. Demographic characteristics, clinical symptoms, signs at the admission, radiological findings, etiologic factors, acute and maintenance treatment, and outcome results were reported. The number of involved sinuses or veins, localizations of thrombus, and lesions on CT and MRI scans were recorded. Results: CH was detected in the brain imaging of 241 (21.1%) patients, as hemorrhagic infarction in 198 patients and intracerebral hemorrhage in 43 patients. Gynecologic causes comprised the largest percentage (41.7%) of etiology and risk factors in the CVST group. In the CH group, headache associated with other neurological symptoms was more frequent. These neurological symptoms were epileptic seizures (46.9%), nausea and/or vomiting (36.5%), altered consciousness (36.5%), and focal neurological deficits (33.6%). mRS was ≥3 in 23.1% of the patients in the CH group. Discussion and Conclusion: CVST, an important cause of stroke in the young, should be monitored closely if the patients have additional symptoms of headache, multiple sinus involvement, and CH. Older age and parenchymal lesion, either hemorrhagic infarction or intracerebral hemorrhage, imply poor outcome. |
doi_str_mv | 10.1159/000510627 |
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Intracerebral hemorrhages occur in approximately one-third of CVST patients. We assessed and compared the findings of the cerebral hemorrhage (CH) group and the CVST group. Materials and Methods: In the VENOST study, medical records of 1,193 patients with CVST, aged over 18 years, were obtained from 35 national stroke centers. Demographic characteristics, clinical symptoms, signs at the admission, radiological findings, etiologic factors, acute and maintenance treatment, and outcome results were reported. The number of involved sinuses or veins, localizations of thrombus, and lesions on CT and MRI scans were recorded. Results: CH was detected in the brain imaging of 241 (21.1%) patients, as hemorrhagic infarction in 198 patients and intracerebral hemorrhage in 43 patients. Gynecologic causes comprised the largest percentage (41.7%) of etiology and risk factors in the CVST group. In the CH group, headache associated with other neurological symptoms was more frequent. These neurological symptoms were epileptic seizures (46.9%), nausea and/or vomiting (36.5%), altered consciousness (36.5%), and focal neurological deficits (33.6%). mRS was ≥3 in 23.1% of the patients in the CH group. Discussion and Conclusion: CVST, an important cause of stroke in the young, should be monitored closely if the patients have additional symptoms of headache, multiple sinus involvement, and CH. Older age and parenchymal lesion, either hemorrhagic infarction or intracerebral hemorrhage, imply poor outcome.</description><identifier>ISSN: 0014-3022</identifier><identifier>EISSN: 1421-9913</identifier><identifier>DOI: 10.1159/000510627</identifier><identifier>PMID: 33130674</identifier><language>eng</language><publisher>Basel, Switzerland</publisher><subject>Adolescent ; Adult ; Aged ; Cerebral Hemorrhage - epidemiology ; Cerebral Hemorrhage - etiology ; Clinical Neurology: Research Article ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Sinus Thrombosis, Intracranial - complications ; Sinus Thrombosis, Intracranial - diagnosis ; Young Adult</subject><ispartof>European neurology, 2020, Vol.83 (6), p.615-621</ispartof><rights>2020 S. Karger AG, Basel</rights><rights>2020 S. Karger AG, Basel.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c334t-bfcd6142293b7d03950c95b9095f18fd41178bfe82bc06089315c05478d10f783</citedby><cites>FETCH-LOGICAL-c334t-bfcd6142293b7d03950c95b9095f18fd41178bfe82bc06089315c05478d10f783</cites><orcidid>0000-0002-4961-4332 ; 0000-0001-5876-8643</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2423,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33130674$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Duman, Taşkın</creatorcontrib><creatorcontrib>Yayla, Vildan</creatorcontrib><creatorcontrib>Uludüz, Derya</creatorcontrib><creatorcontrib>Özaydın Göksu, Eylem</creatorcontrib><creatorcontrib>Yürekli, Vedat Ali</creatorcontrib><creatorcontrib>Genç, Hamit</creatorcontrib><creatorcontrib>Utku, Uygar</creatorcontrib><creatorcontrib>Çınar, Nilgün</creatorcontrib><creatorcontrib>Tekeli, Hakan</creatorcontrib><creatorcontrib>Sungur, Mehmet Ali</creatorcontrib><creatorcontrib>Tokuç, Firdevs Ezgi</creatorcontrib><creatorcontrib>Uzuner, Nevzat</creatorcontrib><creatorcontrib>Şenol, Mehmet Güney</creatorcontrib><creatorcontrib>Yılmaz, Arda</creatorcontrib><creatorcontrib>Gökçe, Mustafa</creatorcontrib><creatorcontrib>Demirci, Seden</creatorcontrib><creatorcontrib>Küsbeci, Özge Yılmaz</creatorcontrib><creatorcontrib>Uzuner, Gülnur Tekgöl</creatorcontrib><creatorcontrib>Şahin, Şevki</creatorcontrib><creatorcontrib>Batur Çağlayan, Hale Zeynep</creatorcontrib><creatorcontrib>Açıkgöz, Mustafa</creatorcontrib><creatorcontrib>Özdağ, Fatih</creatorcontrib><creatorcontrib>Baybaş, Sevim</creatorcontrib><creatorcontrib>Ekmekçi, Hakan</creatorcontrib><creatorcontrib>Çabalar, Murat</creatorcontrib><creatorcontrib>Yaman, Mehmet</creatorcontrib><creatorcontrib>Bektaş, Hesna</creatorcontrib><creatorcontrib>Kaplan, Yüksel</creatorcontrib><creatorcontrib>Göksel, Başak Karakurum</creatorcontrib><creatorcontrib>Milanlıoğlu, Aysel</creatorcontrib><creatorcontrib>Necioğlu Örken, Dilek</creatorcontrib><creatorcontrib>Aluçlu, Mehmet Ufuk</creatorcontrib><creatorcontrib>Çolakoğlu, Sena</creatorcontrib><creatorcontrib>Tüfekçi, Ahmet</creatorcontrib><creatorcontrib>Bakar, Mustafa</creatorcontrib><creatorcontrib>Nazlıel, Bijrn</creatorcontrib><creatorcontrib>Taşçılar, Nida</creatorcontrib><creatorcontrib>Göksan, Baki</creatorcontrib><creatorcontrib>Kozak, Hasan Hüseyin</creatorcontrib><creatorcontrib>Mısırlı, Handan</creatorcontrib><creatorcontrib>Küçükoğlu, Hayriye</creatorcontrib><creatorcontrib>Midi, İpek</creatorcontrib><creatorcontrib>Mengüllüoğlu, Necdet</creatorcontrib><creatorcontrib>Aytaç, Emrah</creatorcontrib><creatorcontrib>Yeşilot, Nilüfer</creatorcontrib><creatorcontrib>İnce, Birsen</creatorcontrib><creatorcontrib>Yalın, Osman Özgür</creatorcontrib><creatorcontrib>Güneş, Taşkın</creatorcontrib><creatorcontrib>Oruç, Serdar</creatorcontrib><creatorcontrib>Mayda Domaç, Füsun</creatorcontrib><creatorcontrib>Öztürk, Şerefnur</creatorcontrib><creatorcontrib>Karahan, Ali</creatorcontrib><creatorcontrib>Erdoğan, Hacı Ali</creatorcontrib><creatorcontrib>Afşar, Nazire</creatorcontrib><title>Assessment of Patients with Intracerebral Hemorrhage or Hemorrhagic Transformation in the VENOST Study</title><title>European neurology</title><addtitle>Eur Neurol</addtitle><description>Introduction: Cerebral venous and sinus thrombosis (CVST) may lead to cerebral edema and increased intracranial pressure; besides, ischemic or hemorrhagic lesions may develop. Intracerebral hemorrhages occur in approximately one-third of CVST patients. We assessed and compared the findings of the cerebral hemorrhage (CH) group and the CVST group. Materials and Methods: In the VENOST study, medical records of 1,193 patients with CVST, aged over 18 years, were obtained from 35 national stroke centers. Demographic characteristics, clinical symptoms, signs at the admission, radiological findings, etiologic factors, acute and maintenance treatment, and outcome results were reported. The number of involved sinuses or veins, localizations of thrombus, and lesions on CT and MRI scans were recorded. Results: CH was detected in the brain imaging of 241 (21.1%) patients, as hemorrhagic infarction in 198 patients and intracerebral hemorrhage in 43 patients. Gynecologic causes comprised the largest percentage (41.7%) of etiology and risk factors in the CVST group. In the CH group, headache associated with other neurological symptoms was more frequent. These neurological symptoms were epileptic seizures (46.9%), nausea and/or vomiting (36.5%), altered consciousness (36.5%), and focal neurological deficits (33.6%). mRS was ≥3 in 23.1% of the patients in the CH group. Discussion and Conclusion: CVST, an important cause of stroke in the young, should be monitored closely if the patients have additional symptoms of headache, multiple sinus involvement, and CH. Older age and parenchymal lesion, either hemorrhagic infarction or intracerebral hemorrhage, imply poor outcome.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Cerebral Hemorrhage - epidemiology</subject><subject>Cerebral Hemorrhage - etiology</subject><subject>Clinical Neurology: Research Article</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Sinus Thrombosis, Intracranial - complications</subject><subject>Sinus Thrombosis, Intracranial - diagnosis</subject><subject>Young Adult</subject><issn>0014-3022</issn><issn>1421-9913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkM9LwzAUx4Mobk4P3kUCXvRQfWmatjmOUd1ANmHTa0nTZKv2x0xSZP-9lc558fTel_f5fuF9EbokcE8I4w8AwAiEfnSEhiTwicc5ocdoCEACj4LvD9CZte-dZDyKT9GAUkIhjIIh0mNrlbWVqh1uNH4RruhWi78Kt8Gz2hkhlVGZESWeqqoxZiPWCjfmTxUSr4yorW5M1bmbGhc1dhuF35L5YrnCS9fmu3N0okVp1cV-jtDrY7KaTL3nxdNsMn72JKWB8zIt87D7wOc0i3KgnIHkLOPAmSaxzgNCojjTKvYzCSHEnBImgQVRnBPQUUxH6LbP3Zrms1XWpVVhpSpLUaumtakfsDAOw5DyDr3rUWkaa43S6dYUlTC7lED6U2t6qLVjr_exbVap_ED-9tgBVz3wIcxamQNw8N_8e07mSU-k21zTb_BShlU</recordid><startdate>2020</startdate><enddate>2020</enddate><creator>Duman, Taşkın</creator><creator>Yayla, Vildan</creator><creator>Uludüz, Derya</creator><creator>Özaydın Göksu, Eylem</creator><creator>Yürekli, Vedat Ali</creator><creator>Genç, Hamit</creator><creator>Utku, Uygar</creator><creator>Çınar, Nilgün</creator><creator>Tekeli, Hakan</creator><creator>Sungur, Mehmet Ali</creator><creator>Tokuç, Firdevs Ezgi</creator><creator>Uzuner, Nevzat</creator><creator>Şenol, Mehmet Güney</creator><creator>Yılmaz, Arda</creator><creator>Gökçe, Mustafa</creator><creator>Demirci, Seden</creator><creator>Küsbeci, Özge Yılmaz</creator><creator>Uzuner, Gülnur Tekgöl</creator><creator>Şahin, Şevki</creator><creator>Batur Çağlayan, Hale Zeynep</creator><creator>Açıkgöz, Mustafa</creator><creator>Özdağ, Fatih</creator><creator>Baybaş, Sevim</creator><creator>Ekmekçi, Hakan</creator><creator>Çabalar, Murat</creator><creator>Yaman, Mehmet</creator><creator>Bektaş, Hesna</creator><creator>Kaplan, Yüksel</creator><creator>Göksel, Başak Karakurum</creator><creator>Milanlıoğlu, Aysel</creator><creator>Necioğlu Örken, Dilek</creator><creator>Aluçlu, Mehmet Ufuk</creator><creator>Çolakoğlu, Sena</creator><creator>Tüfekçi, Ahmet</creator><creator>Bakar, Mustafa</creator><creator>Nazlıel, Bijrn</creator><creator>Taşçılar, 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Transformation in the VENOST Study</title><author>Duman, Taşkın ; Yayla, Vildan ; Uludüz, Derya ; Özaydın Göksu, Eylem ; Yürekli, Vedat Ali ; Genç, Hamit ; Utku, Uygar ; Çınar, Nilgün ; Tekeli, Hakan ; Sungur, Mehmet Ali ; Tokuç, Firdevs Ezgi ; Uzuner, Nevzat ; Şenol, Mehmet Güney ; Yılmaz, Arda ; Gökçe, Mustafa ; Demirci, Seden ; Küsbeci, Özge Yılmaz ; Uzuner, Gülnur Tekgöl ; Şahin, Şevki ; Batur Çağlayan, Hale Zeynep ; Açıkgöz, Mustafa ; Özdağ, Fatih ; Baybaş, Sevim ; Ekmekçi, Hakan ; Çabalar, Murat ; Yaman, Mehmet ; Bektaş, Hesna ; Kaplan, Yüksel ; Göksel, Başak Karakurum ; Milanlıoğlu, Aysel ; Necioğlu Örken, Dilek ; Aluçlu, Mehmet Ufuk ; Çolakoğlu, Sena ; Tüfekçi, Ahmet ; Bakar, Mustafa ; Nazlıel, Bijrn ; Taşçılar, Nida ; Göksan, Baki ; Kozak, Hasan Hüseyin ; Mısırlı, Handan ; Küçükoğlu, Hayriye ; Midi, İpek ; Mengüllüoğlu, Necdet ; Aytaç, Emrah ; Yeşilot, Nilüfer ; İnce, Birsen ; Yalın, Osman Özgür ; Güneş, Taşkın ; Oruç, Serdar ; Mayda Domaç, Füsun ; Öztürk, Şerefnur ; Karahan, 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Vildan</creatorcontrib><creatorcontrib>Uludüz, Derya</creatorcontrib><creatorcontrib>Özaydın Göksu, Eylem</creatorcontrib><creatorcontrib>Yürekli, Vedat Ali</creatorcontrib><creatorcontrib>Genç, Hamit</creatorcontrib><creatorcontrib>Utku, Uygar</creatorcontrib><creatorcontrib>Çınar, Nilgün</creatorcontrib><creatorcontrib>Tekeli, Hakan</creatorcontrib><creatorcontrib>Sungur, Mehmet Ali</creatorcontrib><creatorcontrib>Tokuç, Firdevs Ezgi</creatorcontrib><creatorcontrib>Uzuner, Nevzat</creatorcontrib><creatorcontrib>Şenol, Mehmet Güney</creatorcontrib><creatorcontrib>Yılmaz, Arda</creatorcontrib><creatorcontrib>Gökçe, Mustafa</creatorcontrib><creatorcontrib>Demirci, Seden</creatorcontrib><creatorcontrib>Küsbeci, Özge Yılmaz</creatorcontrib><creatorcontrib>Uzuner, Gülnur Tekgöl</creatorcontrib><creatorcontrib>Şahin, Şevki</creatorcontrib><creatorcontrib>Batur Çağlayan, Hale Zeynep</creatorcontrib><creatorcontrib>Açıkgöz, Mustafa</creatorcontrib><creatorcontrib>Özdağ, Fatih</creatorcontrib><creatorcontrib>Baybaş, Sevim</creatorcontrib><creatorcontrib>Ekmekçi, Hakan</creatorcontrib><creatorcontrib>Çabalar, Murat</creatorcontrib><creatorcontrib>Yaman, Mehmet</creatorcontrib><creatorcontrib>Bektaş, Hesna</creatorcontrib><creatorcontrib>Kaplan, Yüksel</creatorcontrib><creatorcontrib>Göksel, Başak Karakurum</creatorcontrib><creatorcontrib>Milanlıoğlu, Aysel</creatorcontrib><creatorcontrib>Necioğlu Örken, Dilek</creatorcontrib><creatorcontrib>Aluçlu, Mehmet Ufuk</creatorcontrib><creatorcontrib>Çolakoğlu, Sena</creatorcontrib><creatorcontrib>Tüfekçi, Ahmet</creatorcontrib><creatorcontrib>Bakar, Mustafa</creatorcontrib><creatorcontrib>Nazlıel, Bijrn</creatorcontrib><creatorcontrib>Taşçılar, Nida</creatorcontrib><creatorcontrib>Göksan, Baki</creatorcontrib><creatorcontrib>Kozak, Hasan Hüseyin</creatorcontrib><creatorcontrib>Mısırlı, Handan</creatorcontrib><creatorcontrib>Küçükoğlu, Hayriye</creatorcontrib><creatorcontrib>Midi, İpek</creatorcontrib><creatorcontrib>Mengüllüoğlu, Necdet</creatorcontrib><creatorcontrib>Aytaç, Emrah</creatorcontrib><creatorcontrib>Yeşilot, Nilüfer</creatorcontrib><creatorcontrib>İnce, Birsen</creatorcontrib><creatorcontrib>Yalın, Osman Özgür</creatorcontrib><creatorcontrib>Güneş, Taşkın</creatorcontrib><creatorcontrib>Oruç, Serdar</creatorcontrib><creatorcontrib>Mayda Domaç, Füsun</creatorcontrib><creatorcontrib>Öztürk, Şerefnur</creatorcontrib><creatorcontrib>Karahan, Ali</creatorcontrib><creatorcontrib>Erdoğan, Hacı Ali</creatorcontrib><creatorcontrib>Afşar, Nazire</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Duman, Taşkın</au><au>Yayla, Vildan</au><au>Uludüz, Derya</au><au>Özaydın Göksu, Eylem</au><au>Yürekli, Vedat Ali</au><au>Genç, Hamit</au><au>Utku, Uygar</au><au>Çınar, Nilgün</au><au>Tekeli, Hakan</au><au>Sungur, Mehmet Ali</au><au>Tokuç, Firdevs Ezgi</au><au>Uzuner, Nevzat</au><au>Şenol, Mehmet Güney</au><au>Yılmaz, Arda</au><au>Gökçe, Mustafa</au><au>Demirci, Seden</au><au>Küsbeci, Özge Yılmaz</au><au>Uzuner, Gülnur Tekgöl</au><au>Şahin, Şevki</au><au>Batur Çağlayan, Hale Zeynep</au><au>Açıkgöz, Mustafa</au><au>Özdağ, Fatih</au><au>Baybaş, Sevim</au><au>Ekmekçi, Hakan</au><au>Çabalar, Murat</au><au>Yaman, Mehmet</au><au>Bektaş, Hesna</au><au>Kaplan, Yüksel</au><au>Göksel, Başak Karakurum</au><au>Milanlıoğlu, Aysel</au><au>Necioğlu Örken, Dilek</au><au>Aluçlu, Mehmet Ufuk</au><au>Çolakoğlu, Sena</au><au>Tüfekçi, Ahmet</au><au>Bakar, Mustafa</au><au>Nazlıel, Bijrn</au><au>Taşçılar, Nida</au><au>Göksan, Baki</au><au>Kozak, Hasan Hüseyin</au><au>Mısırlı, Handan</au><au>Küçükoğlu, Hayriye</au><au>Midi, İpek</au><au>Mengüllüoğlu, Necdet</au><au>Aytaç, Emrah</au><au>Yeşilot, Nilüfer</au><au>İnce, Birsen</au><au>Yalın, Osman Özgür</au><au>Güneş, Taşkın</au><au>Oruç, Serdar</au><au>Mayda Domaç, Füsun</au><au>Öztürk, Şerefnur</au><au>Karahan, Ali</au><au>Erdoğan, Hacı Ali</au><au>Afşar, Nazire</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of Patients with Intracerebral Hemorrhage or Hemorrhagic Transformation in the VENOST Study</atitle><jtitle>European neurology</jtitle><addtitle>Eur Neurol</addtitle><date>2020</date><risdate>2020</risdate><volume>83</volume><issue>6</issue><spage>615</spage><epage>621</epage><pages>615-621</pages><issn>0014-3022</issn><eissn>1421-9913</eissn><abstract>Introduction: Cerebral venous and sinus thrombosis (CVST) may lead to cerebral edema and increased intracranial pressure; besides, ischemic or hemorrhagic lesions may develop. Intracerebral hemorrhages occur in approximately one-third of CVST patients. We assessed and compared the findings of the cerebral hemorrhage (CH) group and the CVST group. Materials and Methods: In the VENOST study, medical records of 1,193 patients with CVST, aged over 18 years, were obtained from 35 national stroke centers. Demographic characteristics, clinical symptoms, signs at the admission, radiological findings, etiologic factors, acute and maintenance treatment, and outcome results were reported. The number of involved sinuses or veins, localizations of thrombus, and lesions on CT and MRI scans were recorded. Results: CH was detected in the brain imaging of 241 (21.1%) patients, as hemorrhagic infarction in 198 patients and intracerebral hemorrhage in 43 patients. Gynecologic causes comprised the largest percentage (41.7%) of etiology and risk factors in the CVST group. In the CH group, headache associated with other neurological symptoms was more frequent. These neurological symptoms were epileptic seizures (46.9%), nausea and/or vomiting (36.5%), altered consciousness (36.5%), and focal neurological deficits (33.6%). mRS was ≥3 in 23.1% of the patients in the CH group. Discussion and Conclusion: CVST, an important cause of stroke in the young, should be monitored closely if the patients have additional symptoms of headache, multiple sinus involvement, and CH. Older age and parenchymal lesion, either hemorrhagic infarction or intracerebral hemorrhage, imply poor outcome.</abstract><cop>Basel, Switzerland</cop><pmid>33130674</pmid><doi>10.1159/000510627</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-4961-4332</orcidid><orcidid>https://orcid.org/0000-0001-5876-8643</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0014-3022 |
ispartof | European neurology, 2020, Vol.83 (6), p.615-621 |
issn | 0014-3022 1421-9913 |
language | eng |
recordid | cdi_karger_primary_510627 |
source | Karger Journals; MEDLINE |
subjects | Adolescent Adult Aged Cerebral Hemorrhage - epidemiology Cerebral Hemorrhage - etiology Clinical Neurology: Research Article Female Humans Male Middle Aged Retrospective Studies Risk Factors Sinus Thrombosis, Intracranial - complications Sinus Thrombosis, Intracranial - diagnosis Young Adult |
title | Assessment of Patients with Intracerebral Hemorrhage or Hemorrhagic Transformation in the VENOST Study |
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