The Effects of SGLT2 Inhibitors on Cardiovascular and Renal Outcomes in Diabetic Patients: A Systematic Review and Meta-Analysis

The Effects of SGLT2 Inhibitors on Cardiovascular and Renal Outcomes in Diabetic Patients: A Systematic Review and Meta-Analysis

Background: Previous meta-analyses demonstrated the benefits of sodium-glucose cotransporter 2 inhibitors (SGLT2i) primarily on patients with established atherosclerotic cardiovascular disease (ASCVD), but with questionable efficacy on patients at risk of ASCVD. Additionally, evidence of beneficial...

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Veröffentlicht in:Cardiorenal medicine 2020-01, Vol.10 (1), p.1-10
Hauptverfasser: Lo, Kevin Bryan, Gul, Fahad, Ram, Pradhum, Kluger, Aaron Y., Tecson, Kristen M., McCullough, Peter A., Rangaswami, Janani
Format: Artikel
Sprache:eng
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Systematic Review
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Zusammenfassung:Background: Previous meta-analyses demonstrated the benefits of sodium-glucose cotransporter 2 inhibitors (SGLT2i) primarily on patients with established atherosclerotic cardiovascular disease (ASCVD), but with questionable efficacy on patients at risk of ASCVD. Additionally, evidence of beneficial cardiorenal outcomes in patients with estimated glomerular filtration rate (eGFR)
ISSN:1664-3828
1664-5502
DOI:10.1159/000503919