Intralesional Cryosurgery to Treat Keloid Scars: Results from a Retrospective Study

Background: A variety of treatment modalities have been proposed to treat keloid scars, but outcomes are often disappointing. Intralesional cryosurgery may significantly reduce these scars. Objective: To evaluate the clinical safety and efficacy of intralesional cryosurgery to treat keloid scars. Fe...

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Veröffentlicht in:Dermatology (Basel) 2014-01, Vol.229 (3), p.263-270
Hauptverfasser: Chopinaud, Marianne, Pham, Anne-Dominique, Labbé, Daniel, Verneuil, Laurence, Gourio, Charlotte, Bénateau, Hervé, Dompmartin, Anne
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Sprache:eng
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Zusammenfassung:Background: A variety of treatment modalities have been proposed to treat keloid scars, but outcomes are often disappointing. Intralesional cryosurgery may significantly reduce these scars. Objective: To evaluate the clinical safety and efficacy of intralesional cryosurgery to treat keloid scars. Feedback from patients on pain, pruritus and aesthetic discomfort was recorded before and after treatment. Methods: A total of 10 patients with 14 keloid scars resistant to conventional treatments were enrolled in a retrospective study between October 2007 and October 2013. The efficacy of this treatment was evaluated by measuring the reduction in scar surface. Results: Scar surface was reduced by an average of 58.5% after intralesional cryosurgery treatment for all scars (average pre-operative keloid scar surface: 874.6 ± 954.1 mm 2 ; average post-operative keloid scar surface: 505.8 ± 1,024.7 mm 2 ; p = 0.002). Pain and aesthetic discomfort were significantly decreased after treatment in all patients (p = 0.008 and p = 0.012, respectively). Conclusion: Our data suggest that intralesional cryosurgery is an effective treatment for keloids.
ISSN:1018-8665
1421-9832
DOI:10.1159/000365392