Acanthosis nigricans with Severe Obesity, Insulin Resistance and Hypothyroidism: Improvement by Diet Control

We report on a 27-year-old man with acanthosis nigricans (AN) associated with severe obesity, insulin resistance and hypothyroidism. A very low-calory diet treatment decreased his weight and then ameliorated the insulin-resistant state. These effects were followed by remarkable improvement of the AN...

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Veröffentlicht in:Dermatology (Basel) 1999-01, Vol.198 (2), p.164-166
Hauptverfasser: Kuroki, R., Sadamoto, Y., Imamura, M., Abe, Y., Higuchi, K., Kato, K., Koga, T., Furue, M.
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container_end_page 166
container_issue 2
container_start_page 164
container_title Dermatology (Basel)
container_volume 198
creator Kuroki, R.
Sadamoto, Y.
Imamura, M.
Abe, Y.
Higuchi, K.
Kato, K.
Koga, T.
Furue, M.
description We report on a 27-year-old man with acanthosis nigricans (AN) associated with severe obesity, insulin resistance and hypothyroidism. A very low-calory diet treatment decreased his weight and then ameliorated the insulin-resistant state. These effects were followed by remarkable improvement of the AN prior to the correction of the hypothyroidism. This confirms that AN may be mainly attributed to insulin resistance rather than hypothyroidism per se.
doi_str_mv 10.1159/000018096
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source Karger Journals; MEDLINE
subjects Acanthosis Nigricans - complications
Acanthosis Nigricans - pathology
Adult
Biological and medical sciences
Case Report
Chronic Disease
Dermatology
Diet, Reducing
Humans
Hypothyroidism - complications
Hypothyroidism - drug therapy
Insulin Resistance
Male
Medical sciences
Obesity - complications
Obesity - diet therapy
Obesity - metabolism
Pigmentary diseases of the skin
Skin - pathology
Thyroiditis - complications
title Acanthosis nigricans with Severe Obesity, Insulin Resistance and Hypothyroidism: Improvement by Diet Control
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