Acanthosis nigricans with Severe Obesity, Insulin Resistance and Hypothyroidism: Improvement by Diet Control

We report on a 27-year-old man with acanthosis nigricans (AN) associated with severe obesity, insulin resistance and hypothyroidism. A very low-calory diet treatment decreased his weight and then ameliorated the insulin-resistant state. These effects were followed by remarkable improvement of the AN...

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Veröffentlicht in:Dermatology (Basel) 1999-01, Vol.198 (2), p.164-166
Hauptverfasser: Kuroki, R., Sadamoto, Y., Imamura, M., Abe, Y., Higuchi, K., Kato, K., Koga, T., Furue, M.
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Sprache:eng
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Zusammenfassung:We report on a 27-year-old man with acanthosis nigricans (AN) associated with severe obesity, insulin resistance and hypothyroidism. A very low-calory diet treatment decreased his weight and then ameliorated the insulin-resistant state. These effects were followed by remarkable improvement of the AN prior to the correction of the hypothyroidism. This confirms that AN may be mainly attributed to insulin resistance rather than hypothyroidism per se.
ISSN:1018-8665
1421-9832
DOI:10.1159/000018096