Acute Kidney Injury of Non-Septic Origin Requiring Dialysis Therapy

Acute kidney injury (AKI) requiring dialysis occurs frequently, and its pathogenesis involves multiple pathways within which hemodynamic, inflammatory and nephrotoxic factors overlap. Several studies have tried to assess the risk factors leading to AKI, and found, among other factors, that preoperat...

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Veröffentlicht in:Contributions to nephrology 2010-01, Vol.166, p.31-39
Hauptverfasser: Suzuki, Hiromichi, Kanno, Yoshihiko, Tsukamoto, Isao, Tsuchiya, Youhei, Sugahara, Soichi
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Sprache:eng
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Zusammenfassung:Acute kidney injury (AKI) requiring dialysis occurs frequently, and its pathogenesis involves multiple pathways within which hemodynamic, inflammatory and nephrotoxic factors overlap. Several studies have tried to assess the risk factors leading to AKI, and found, among other factors, that preoperative renal dysfunction is important. Currently, it is uncertain when dialysis therapy should start. However, AKI after cardiac surgery should be treated early by continuous hemodialysis.
ISSN:0302-5144
1662-2782
DOI:10.1159/000314850