THE EFFECTS OF A SPIRONOLACTONE AND ESTROGEN IN SALT DEFICIENT RABBITS
Male rabbits deprived of food develop a polyuric-polydipsic syndrome which is due to a renal salt loss. This syndrome is inhibited by estrogen administration. To determine whether adrenal mediation is involved in this estrogen effect, the influence of a spironolactone which blocks the peripheral act...
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| Veröffentlicht in: | Proceedings of the Pennsylvania Academy of Science 1966-06, Vol.39 (2), p.170-174 |
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| container_title | Proceedings of the Pennsylvania Academy of Science |
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| creator | Nocenti, M. R. Cizek, L. J. Aronoff, M. S. Pieri, C. M. |
| description | Male rabbits deprived of food develop a polyuric-polydipsic syndrome which is due to a renal salt loss. This syndrome is inhibited by estrogen administration. To determine whether adrenal mediation is involved in this estrogen effect, the influence of a spironolactone which blocks the peripheral action of aldosterone was studied. Aldactone alone caused a marked increase in sodium loss. Aldactone did not abolish the depressed fluid exchange due to estrogen administration. |
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Aldactone did not abolish the depressed fluid exchange due to estrogen administration.</description><subject>Body weight</subject><subject>Estrogens</subject><subject>Excretion</subject><subject>Food deprivation</subject><subject>INVESTIGATIONS IN BIOLOGICAL SCIENCES</subject><subject>Mineralocorticoids</subject><subject>Salts</subject><subject>Sodium</subject><subject>Steroids</subject><subject>Table salt</subject><subject>Urine</subject><issn>0096-9222</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1966</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqFyTEKwjAUANAMChbtEYR_gUJSY7Vjmv7YQEkk-XvpoGBRlMbF27u4O73hLVjGeV0VdVmWK5anNHHOxZFX8iAyZqhDQGNQUwRvQEE82-Cd75Um7xCUawEjBX9CB9ZBVD1Bi8Zqi44gqKaxFDdseR3v6ZL_XLOtQdJdMaX3cx5e8-0xzp9BSiG43Fe7f_8FkxkvfQ</recordid><startdate>19660601</startdate><enddate>19660601</enddate><creator>Nocenti, M. R.</creator><creator>Cizek, L. J.</creator><creator>Aronoff, M. S.</creator><creator>Pieri, C. 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To determine whether adrenal mediation is involved in this estrogen effect, the influence of a spironolactone which blocks the peripheral action of aldosterone was studied. Aldactone alone caused a marked increase in sodium loss. Aldactone did not abolish the depressed fluid exchange due to estrogen administration.</abstract><pub>Pennsylvania Academy of Science</pub></addata></record> |
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| ispartof | Proceedings of the Pennsylvania Academy of Science, 1966-06, Vol.39 (2), p.170-174 |
| issn | 0096-9222 |
| language | eng |
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| source | Jstor Complete Legacy |
| subjects | Body weight Estrogens Excretion Food deprivation INVESTIGATIONS IN BIOLOGICAL SCIENCES Mineralocorticoids Salts Sodium Steroids Table salt Urine |
| title | THE EFFECTS OF A SPIRONOLACTONE AND ESTROGEN IN SALT DEFICIENT RABBITS |
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