Kinetics of Antibody Concentration and Avidity for the Assessment of Immune Response to Pneumococcal Vaccine among Children with Bone Marrow

Kinetics of Antibody Concentration and Avidity for the Assessment of Immune Response to Pneumococcal Vaccine among Children with Bone Marrow

The kinetics of the immune response to the 23-valent pneumococcal polysaccharide vaccine (PPV) were studied in 38 children who received bone marrow transplants (BMTs). Antipneumococcal antibody concentrations increased 1 and 3 months after vaccination for all 5 serotypes tested, but, in 21 children,...

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Veröffentlicht in:The Journal of infectious diseases 2000-09, Vol.182 (3), p.965-969
Hauptverfasser: Spoulou, Vana, Victoratos, Panayiotis, Ioannidis, John P. A., Grafakos, Stelios
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies
Antibody affinity
Bone marrow
Concise Communications
Conjugate vaccines
Immune response
Kinetics
Older adults
Pneumococcal vaccine
Polysaccharides
Vaccination
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Zusammenfassung:The kinetics of the immune response to the 23-valent pneumococcal polysaccharide vaccine (PPV) were studied in 38 children who received bone marrow transplants (BMTs). Antipneumococcal antibody concentrations increased 1 and 3 months after vaccination for all 5 serotypes tested, but, in 21 children, the vaccine was not adequately immunogenic. Children vaccinated
ISSN:0022-1899