Biological Monitoring of Workers Exposed to Acetone in AcetateFibre Plants

Concentrations of acetone in urine, alveolar air, and blood were measured by gas chromatography with flame ionisation detection for 110 subjects occupationally exposed to acetone (mean 372 ppm) in three factories. Significant relations were found between the time weighted average environmental conce...

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Veröffentlicht in:	British journal of industrial medicine 1992-09, Vol.49 (9), p.654-657
Hauptverfasser:	Fujino, Akihiro, Satoh, Toshihiko, Takebayashi, Tohru, Nakashima, Hiroshi, Sakurai, Haruhiko, Higashi, Toshiaki, Matumura, Hiroshi, Minaguchi, Haruo, Kawai, Toshio
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates Air sampling Alveolar air Blood Chemical hazards Environmental assessment Excretion Liquids Solvents Urine
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Zusammenfassung:	Concentrations of acetone in urine, alveolar air, and blood were measured by gas chromatography with flame ionisation detection for 110 subjects occupationally exposed to acetone (mean 372 ppm) in three factories. Significant relations were found between the time weighted average environmental concentration and the concentration in the biological samples. The strongest correlation was between the concentration of acetone in urine and the degree of exposure (r = 0·71, 95% CI 0·64–0·77). This suggests that urinary acetone concentration is the best biological index of occupational exposure to acetone.
ISSN:	0007-1072