Developmental Physiology of Cestodes. XIII. Vitamin B6 Requirement of Hymenolepis diminuta during In vitro Cultivation

Developmental Physiology of Cestodes. XIII. Vitamin B6 Requirement of Hymenolepis diminuta during In vitro Cultivation

The effects of an antimetabolite of vitamin B6, 4-deoxypyridoxine HCl, on the in vitro development of Hymenolepis diminuta (Cestoda: Cyclophyllidea) were observed. A high concentration of deoxypyridoxine in the cultivation medium (400 μ M initial concentration in balanced salt solution overlay) comp...

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Veröffentlicht in:The Journal of parasitology 1973-02, Vol.59 (1), p.101-104
Hauptverfasser: Roberts, Larry S., Mong, Faith N.
Format: Artikel
Sprache:eng
Schlagworte:
Antimetabolites
Blood
Cysticercoids
Parasite hosts
Parasitism
Parasitology
Phosphates
Physiology
Tapeworms
Worms
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Zusammenfassung:The effects of an antimetabolite of vitamin B6, 4-deoxypyridoxine HCl, on the in vitro development of Hymenolepis diminuta (Cestoda: Cyclophyllidea) were observed. A high concentration of deoxypyridoxine in the cultivation medium (400 μ M initial concentration in balanced salt solution overlay) completely inhibited growth and reproduction by the tapeworm, and the inhibition was entirely reversed by the presence of equimolar pyridoxine. The results strongly support the thesis that H. diminuta has a direct nutritional requirement for an external source of vitamin B6.
ISSN:0022-3395
1937-2345