Isolation and Characterization of a Trisiallactosylceramide, GT3, Containing an O-Acetylated Silaic Acid in Cod Fish Brain

Isolation and Characterization of a Trisiallactosylceramide, GT3, Containing an O-Acetylated Silaic Acid in Cod Fish Brain

An O-acetylated ganglioside that generated a trisialyllactosylceramide or GT3 by base treatment was found for the first time in cod fish brain. This ganglioside was isolated by high-performance liquid chromatography, and characterized by fast atom bombardment mass spectrometry, and proton nuclear ma...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of biochemistry (Tokyo) 1993-04, Vol.113 (4), p.502-507
Hauptverfasser: Waki, Hastue, Murata, Akane, Kon, Kazuo, Maruyama, Kazuaki, Kimura, Shoji, Ogura, Haruo, Ando, Susumu
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 507
container_issue 4
container_start_page 502
container_title Journal of biochemistry (Tokyo)
container_volume 113
creator Waki, Hastue
Murata, Akane
Kon, Kazuo
Maruyama, Kazuaki
Kimura, Shoji
Ogura, Haruo
Ando, Susumu
description An O-acetylated ganglioside that generated a trisialyllactosylceramide or GT3 by base treatment was found for the first time in cod fish brain. This ganglioside was isolated by high-performance liquid chromatography, and characterized by fast atom bombardment mass spectrometry, and proton nuclear magnetic resonance spectroscopy in addition to chemical analysis. The structure was identified as a modified GT3 in which the external sialic acid is O-acetylated at the C-9 position. The chemical structure is as follows: H3(9- O-Ac-NeuAc2-8NeuAc2-8NeuAc2-3)Lac Cer.
doi_str_mv 10.1093/oxfordjournals.jbchem.a124073
format Article
fullrecord <record><control><sourceid>istex</sourceid><recordid>TN_cdi_istex_primary_ark_67375_HXZ_BLN2TGJ6_P</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ark_67375_HXZ_BLN2TGJ6_P</sourcerecordid><originalsourceid>FETCH-LOGICAL-i106t-e3ad40ca2777bdb47a55ccb4ba6e31d32f36556cf17e5df5e1194130a321d25f3</originalsourceid><addsrcrecordid>eNotjktPwzAQhH0AiVL4D75wa4ofcawe24g-UEWRCFLFJdrYDt2SxsgOUttfT1A5jWZn9tMQ8sDZmLOJfPTH2ge79z-hhSaO95XZucMYuEiZlldkwJjgyUSk2xtyG-P-zwopB-S8ir6BDn1LobU030EA07mA58vR1xRoETAiNE2f-HhqjAtwQOtGdFHIEc192wG22H72CLpJpsZ1p57pLH3DBtDQqUFLse2bls4x7ugs9A935Lrut7r7fx2S9_lTkS-T9WaxyqfrBDnLusRJsCkzILTWla1SDUoZU6UVZE5yK0UtM6UyU3PtlK2V43yScslACm6FquWQJBcuxs4dy--ABwinEsJXmWmpVbncfpSz9YsoFs9Z-Sp_AQHUaAM</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Isolation and Characterization of a Trisiallactosylceramide, GT3, Containing an O-Acetylated Silaic Acid in Cod Fish Brain</title><source>Oxford University Press Journals Digital Archive legacy</source><source>J-STAGE (Japan Science &amp; Technology Information Aggregator, Electronic) Freely Available Titles - Japanese</source><source>Free Full-Text Journals in Chemistry</source><creator>Waki, Hastue ; Murata, Akane ; Kon, Kazuo ; Maruyama, Kazuaki ; Kimura, Shoji ; Ogura, Haruo ; Ando, Susumu</creator><creatorcontrib>Waki, Hastue ; Murata, Akane ; Kon, Kazuo ; Maruyama, Kazuaki ; Kimura, Shoji ; Ogura, Haruo ; Ando, Susumu</creatorcontrib><description>An O-acetylated ganglioside that generated a trisialyllactosylceramide or GT3 by base treatment was found for the first time in cod fish brain. This ganglioside was isolated by high-performance liquid chromatography, and characterized by fast atom bombardment mass spectrometry, and proton nuclear magnetic resonance spectroscopy in addition to chemical analysis. The structure was identified as a modified GT3 in which the external sialic acid is O-acetylated at the C-9 position. The chemical structure is as follows: H3(9- O-Ac-NeuAc2-8NeuAc2-8NeuAc2-3)Lac Cer.</description><identifier>ISSN: 0021-924X</identifier><identifier>DOI: 10.1093/oxfordjournals.jbchem.a124073</identifier><language>eng</language><publisher>Oxford University Press</publisher><ispartof>Journal of biochemistry (Tokyo), 1993-04, Vol.113 (4), p.502-507</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Waki, Hastue</creatorcontrib><creatorcontrib>Murata, Akane</creatorcontrib><creatorcontrib>Kon, Kazuo</creatorcontrib><creatorcontrib>Maruyama, Kazuaki</creatorcontrib><creatorcontrib>Kimura, Shoji</creatorcontrib><creatorcontrib>Ogura, Haruo</creatorcontrib><creatorcontrib>Ando, Susumu</creatorcontrib><title>Isolation and Characterization of a Trisiallactosylceramide, GT3, Containing an O-Acetylated Silaic Acid in Cod Fish Brain</title><title>Journal of biochemistry (Tokyo)</title><description>An O-acetylated ganglioside that generated a trisialyllactosylceramide or GT3 by base treatment was found for the first time in cod fish brain. This ganglioside was isolated by high-performance liquid chromatography, and characterized by fast atom bombardment mass spectrometry, and proton nuclear magnetic resonance spectroscopy in addition to chemical analysis. The structure was identified as a modified GT3 in which the external sialic acid is O-acetylated at the C-9 position. The chemical structure is as follows: H3(9- O-Ac-NeuAc2-8NeuAc2-8NeuAc2-3)Lac Cer.</description><issn>0021-924X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><recordid>eNotjktPwzAQhH0AiVL4D75wa4ofcawe24g-UEWRCFLFJdrYDt2SxsgOUttfT1A5jWZn9tMQ8sDZmLOJfPTH2ge79z-hhSaO95XZucMYuEiZlldkwJjgyUSk2xtyG-P-zwopB-S8ir6BDn1LobU030EA07mA58vR1xRoETAiNE2f-HhqjAtwQOtGdFHIEc192wG22H72CLpJpsZ1p57pLH3DBtDQqUFLse2bls4x7ugs9A935Lrut7r7fx2S9_lTkS-T9WaxyqfrBDnLusRJsCkzILTWla1SDUoZU6UVZE5yK0UtM6UyU3PtlK2V43yScslACm6FquWQJBcuxs4dy--ABwinEsJXmWmpVbncfpSz9YsoFs9Z-Sp_AQHUaAM</recordid><startdate>199304</startdate><enddate>199304</enddate><creator>Waki, Hastue</creator><creator>Murata, Akane</creator><creator>Kon, Kazuo</creator><creator>Maruyama, Kazuaki</creator><creator>Kimura, Shoji</creator><creator>Ogura, Haruo</creator><creator>Ando, Susumu</creator><general>Oxford University Press</general><scope>BSCLL</scope></search><sort><creationdate>199304</creationdate><title>Isolation and Characterization of a Trisiallactosylceramide, GT3, Containing an O-Acetylated Silaic Acid in Cod Fish Brain</title><author>Waki, Hastue ; Murata, Akane ; Kon, Kazuo ; Maruyama, Kazuaki ; Kimura, Shoji ; Ogura, Haruo ; Ando, Susumu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i106t-e3ad40ca2777bdb47a55ccb4ba6e31d32f36556cf17e5df5e1194130a321d25f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Waki, Hastue</creatorcontrib><creatorcontrib>Murata, Akane</creatorcontrib><creatorcontrib>Kon, Kazuo</creatorcontrib><creatorcontrib>Maruyama, Kazuaki</creatorcontrib><creatorcontrib>Kimura, Shoji</creatorcontrib><creatorcontrib>Ogura, Haruo</creatorcontrib><creatorcontrib>Ando, Susumu</creatorcontrib><collection>Istex</collection><jtitle>Journal of biochemistry (Tokyo)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Waki, Hastue</au><au>Murata, Akane</au><au>Kon, Kazuo</au><au>Maruyama, Kazuaki</au><au>Kimura, Shoji</au><au>Ogura, Haruo</au><au>Ando, Susumu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Isolation and Characterization of a Trisiallactosylceramide, GT3, Containing an O-Acetylated Silaic Acid in Cod Fish Brain</atitle><jtitle>Journal of biochemistry (Tokyo)</jtitle><date>1993-04</date><risdate>1993</risdate><volume>113</volume><issue>4</issue><spage>502</spage><epage>507</epage><pages>502-507</pages><issn>0021-924X</issn><abstract>An O-acetylated ganglioside that generated a trisialyllactosylceramide or GT3 by base treatment was found for the first time in cod fish brain. This ganglioside was isolated by high-performance liquid chromatography, and characterized by fast atom bombardment mass spectrometry, and proton nuclear magnetic resonance spectroscopy in addition to chemical analysis. The structure was identified as a modified GT3 in which the external sialic acid is O-acetylated at the C-9 position. The chemical structure is as follows: H3(9- O-Ac-NeuAc2-8NeuAc2-8NeuAc2-3)Lac Cer.</abstract><pub>Oxford University Press</pub><doi>10.1093/oxfordjournals.jbchem.a124073</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0021-924X
ispartof Journal of biochemistry (Tokyo), 1993-04, Vol.113 (4), p.502-507
issn 0021-924X
language eng
recordid cdi_istex_primary_ark_67375_HXZ_BLN2TGJ6_P
source Oxford University Press Journals Digital Archive legacy; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Free Full-Text Journals in Chemistry
title Isolation and Characterization of a Trisiallactosylceramide, GT3, Containing an O-Acetylated Silaic Acid in Cod Fish Brain
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T09%3A58%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-istex&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Isolation%20and%20Characterization%20of%20a%20Trisiallactosylceramide,%20GT3,%20Containing%20an%20O-Acetylated%20Silaic%20Acid%20in%20Cod%20Fish%20Brain&rft.jtitle=Journal%20of%20biochemistry%20(Tokyo)&rft.au=Waki,%20Hastue&rft.date=1993-04&rft.volume=113&rft.issue=4&rft.spage=502&rft.epage=507&rft.pages=502-507&rft.issn=0021-924X&rft_id=info:doi/10.1093/oxfordjournals.jbchem.a124073&rft_dat=%3Cistex%3Eark_67375_HXZ_BLN2TGJ6_P%3C/istex%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true