Shape-Controlled Synthesis of Sulfur-Doped Co3O4 for Enhanced Nonenzymatic Detection of Glucose

Co3O4 with different morphologies were synthesized for electrochemical sensing of glucose. Various morphologies of Co3O4 were fabricated using a facile approach by adjusting solvent. The morphology and composition of Co3O4 were characterized by scanning electron microscopy (SEM) and X-ray diffraction spectroscopy (XRD). The electrochemical properties of various Co3O4 structures were studied, which shows that nanoporous nanosheets-like Co3O4 exhibits higher electrocatalytic activity toward glucose oxidation. Then, S was doped into nanoporous nanosheets-like Co3O4 through a hydrothermal process and the results display that S doping strategy significantly improves electrocatalytic activity of Co3O4 for glucose oxidation. An excellent analytical performances with a high sensitivity of 648.7 mA mM −1 cm−2, a low detection limit of 0.7 M and a linear range from 2.0 M to 3.11 mM are obtained, demonstrating that S-doped Co3O4 is an efficient material for electrochemical sensing of glucose.