Plasmonic Nanopore Fabrication for Single Molecule Bio Sensor Using Electron Beam Irradiation

About sixty years ago, the biological cell counter with an electrical detection technique through a micrometer size orifice was invented by Dr. Coulter. Recently, the ultrafast portable pore device (MinION) with an electrical detection technique was manufactured by Oxford Nanopore Technology. However, high error rates possibly from the electrical double layer formed in the pore channel is initially reported in several journals. Furthermore, considering the fact that the optical detection technique is being utilized in the biosensors, the optical pore device can be an excellent candidate for the next generation single molecule sensor. We will report the fabrication process of the plasmonic optical nanopores.