Similarity of solid state structures of R- and S-isomers of clopidogrel hydrogensulphate salt

Similarity of solid state structures of R- and S-isomers of clopidogrel hydrogensulphate salt

The present study showed, that the crystal structures of R-isomer and the polymorphic form 1 of clopidrogrel hydrogensulphate S-isomer are very similar.

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Bibliographische Detailangaben
Veröffentlicht in:Pharmazie 2010-05, Vol.65 (5), p.389-390
Hauptverfasser: Zupančič, V., Kotar-Jordan, B., Plevnik, M., Smrkolj, M., Vrečer, F.
Format: Artikel
Sprache:eng
Schlagworte:
Calorimetry, Differential Scanning
Crystallization
Hydrogen Bonding
Indicators and Reagents
Magnetic Resonance Spectroscopy
Optical Rotation
Platelet Aggregation Inhibitors - chemistry
Solvents
Spectroscopy, Fourier Transform Infrared
Stereoisomerism
Ticlopidine - analogs & derivatives
Ticlopidine - chemistry
X-Ray Diffraction
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Beschreibung
Zusammenfassung:The present study showed, that the crystal structures of R-isomer and the polymorphic form 1 of clopidrogrel hydrogensulphate S-isomer are very similar.
ISSN:0031-7144
DOI:10.1691/ph.2010.9345