Complete Remission of 4 Years Following Autologous Blood Stem Cell Transplantation in a Child with Early Relapse of Translocation T(9;X) Acute Lymphoblastic Leukemia

A survey of the International Bone Marrow Registry (IBMTR) in 1987 showed that the chance for continuous complete remission (CR) in children after a relapse of acute lymphoblastic leukemia (ALL) within 18 months after initial diagnosis is less than 5% with conventional chemotherapy and about 20% wit...

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Veröffentlicht in:	Pediatric hematology and oncology 1992, Vol.9 (3), p.273-275
Hauptverfasser:	Emminger, Wolfgang, Emminger-Schmidmeier, Waltraud, Haas, Oscar A., Höcker, Paul, Hawliczek, Robert, Peters, Christina, Gadner, Helmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Child, Preschool Chromosomes, Human, Pair 9 Follow-Up Studies Hematopoietic Stem Cell Transplantation Humans Male Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy Recurrence Remission Induction - methods Time Factors Translocation, Genetic - genetics Transplantation, Autologous
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Zusammenfassung:	A survey of the International Bone Marrow Registry (IBMTR) in 1987 showed that the chance for continuous complete remission (CR) in children after a relapse of acute lymphoblastic leukemia (ALL) within 18 months after initial diagnosis is less than 5% with conventional chemotherapy and about 20% with allogeneic bone marrow transplantation (alloBMT).1 Results have not improved in the meantime.2 More recently, infusion of blood-derived stem cells (ABSCT) after myeloablative treatment was followed by complete hematopoietic reconstitution in both adults and pediatric cancer patients.3-6
ISSN:	0888-0018 1521-0669
DOI:	10.3109/08880019209016596