Assignment of the mouse alpha A-crystallin structural gene to chromosome 17

αA2-crystallin is one of the major water-soluble proteins of the mammalian lens. Using a cloned cDNA probe coding for mouse αA2-crystallin and Southern blot hybridization, DNA isolated from a panel of somatic cell hybrids prepared from mouse fibroblasts or mouse spleen cells fused with Chinese hamst...

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Veröffentlicht in:	Current eye research 1985, Vol.4 (12), p.1263-1268
Hauptverfasser:	Kaye, Nancy Weber, Church, Robert L., Piatigorsky, Joram, Petrash, J. Mark, Lalley, Peter A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Line Chromosome Mapping Classical genetics, quantitative genetics, hybrids Cricetinae Cricetulus Crystallins - genetics DNA, Circular Fundamental and applied biological sciences. Psychology Genes Genetics of eukaryotes. Biological and molecular evolution Hybrid Cells Mice - genetics Mice, Inbred BALB C Vertebrata
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Beschreibung
Zusammenfassung:	αA2-crystallin is one of the major water-soluble proteins of the mammalian lens. Using a cloned cDNA probe coding for mouse αA2-crystallin and Southern blot hybridization, DNA isolated from a panel of somatic cell hybrids prepared from mouse fibroblasts or mouse spleen cells fused with Chinese hamster fibroblasts was probed to determine the chromosomal localization of the αA2-crystallin structural gene. We have located this gene on mouse chromosome 17.
ISSN:	0271-3683 1460-2202
DOI:	10.3109/02713688509017685