Cortical blindness and occipital lobe seizures induced by cis-platinum

Cortical blindness and occipital lobe seizures induced by cis-platinum

Three patients developed occipital lobe seizures as a manifestation of diaminodichloro platinum (DDP) toxicity. They were characterized in two patients by cortical blindness, ictal nystagmus and a confusional state. The third patient had visual hallucinations followed by grand mal seizures. All the...

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Veröffentlicht in:Neuro-ophthalmology (Amsterdam : Aeolus Press. 1980) 1987, Vol.7 (2), p.99-104
Hauptverfasser: Kattah, Jorge c., Potolicchio, Samuel J., Kotz, Herbert L., Kolsky, Martin P., Thomas, David
Format: Artikel
Sprache:eng
Schlagworte:
ictal nystagmus
platinum neurotoxicity
transient cortical blindness
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Zusammenfassung:Three patients developed occipital lobe seizures as a manifestation of diaminodichloro platinum (DDP) toxicity. They were characterized in two patients by cortical blindness, ictal nystagmus and a confusional state. The third patient had visual hallucinations followed by grand mal seizures. All the abnormalities in these patients responded to anticonvulsant therapy.
ISSN:0165-8107
1744-506X
DOI:10.3109/01658108709007436