Poor Response to Long-term Albendazole Therapy of Hydatid Liver Cysts

Seven patients with uncomplicated hepatic hydatid cysts (Echinococcus granulosus) were treated with albendazole 10 mg/kg/day for 2-6 months (mean 4 months). Serial sonographic evaluation showed reduction in cyst size in only 1 patient (the anteroposterior diameter decreased from 16.5 cm to 4.9 cm)....

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Veröffentlicht in:	Scandinavian journal of infectious diseases 1989, Vol.21 (3), p.323-325
Hauptverfasser:	Choudhuri, Gourdas, Prasad, Rajendranath, Tantry, Bailur V., Sharma, Mahesh P., Tandon, Rakesh K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Albendazole Anthelmintics - therapeutic use Benzimidazoles - adverse effects Benzimidazoles - therapeutic use Biological and medical sciences Diseases caused by cestodes Drug Evaluation Echinococcoses Echinococcosis, Hepatic - blood Echinococcosis, Hepatic - drug therapy Echinococcosis, Hepatic - pathology Female Follow-Up Studies Gastroenterology. Liver. Pancreas. Abdomen Helminthic diseases Humans Infectious diseases Liver - pathology Male Medical sciences Middle Aged Parasitic diseases Tropical medicine Ultrasonography
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Zusammenfassung:	Seven patients with uncomplicated hepatic hydatid cysts (Echinococcus granulosus) were treated with albendazole 10 mg/kg/day for 2-6 months (mean 4 months). Serial sonographic evaluation showed reduction in cyst size in only 1 patient (the anteroposterior diameter decreased from 16.5 cm to 4.9 cm). Therapy in this patient was discontinued after 4 months due to development of jaundice. Albendazole appears to have a limited role in the treatment of hydatid disease of the liver.
ISSN:	0036-5548 1651-1980
DOI:	10.3109/00365548909035703