Coordination Compounds of Uranyl(II) Ion with Some Selected Antibiotics

The formation of the complexes between uranyl(II) ion with ampicillin, cephalexin and cephradine has been investigated using potentiometric technique. The stability constants of the complexes formed were calculated using the non-linear least-square computer program MINIQUAD. The uranyl(II) complexes with the antibiotics were synthesised and characterized by elemental analyses, conductivity and IR spectroscopy. From theses studies it is proposed that the antibiotic acts as a bidentate ligand and is bound to the metal ion through the carbonyl and the amino groups of the side chain.