Antihyperlipidemic effect of aqueous extract of Plumbago zeylanica roots in diet-induced hyperlipidemic rat

This study examined the antihyperlipidemic effect of the aqueous extract of Plumbago zeylanica Linn. (Plumbaginaceae) roots in diet-induced hyperlipidemic rats. The oral administration of the aqueous extract at the dose of 20, 40, and 80 mg kg−1 were found to ameliorate the hyperlipidemic condition...

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Veröffentlicht in:Pharmaceutical biology 2009-10, Vol.47 (10), p.1004-1010
Hauptverfasser: Pendurkar, Sudha R., Mengi, Sushma A.
Format: Artikel
Sprache:eng
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Zusammenfassung:This study examined the antihyperlipidemic effect of the aqueous extract of Plumbago zeylanica Linn. (Plumbaginaceae) roots in diet-induced hyperlipidemic rats. The oral administration of the aqueous extract at the dose of 20, 40, and 80 mg kg−1 were found to ameliorate the hyperlipidemic condition as evidenced by a reduction of cholesterol and triglyceride levels. The standards fenofibrate (20 mg kg−1) and atorvastatin (8 mg kg−1) were also found to exhibit significant (p 
ISSN:1388-0209
1744-5116
DOI:10.1080/13880200902973779