Botulinum toxin treatment for a compensatory hyperhidrosis subsequent to an upper thoracic sympathectomy

BACKGROUND : Compensatory hyperhidrosis is the commonest complication of sympathectomy, but there's no known effective treatment. METHODS : Botulinum toxin type A (a total dose of 300 MU, 1.0 MU/cm 2 ) was used successfully to treat a 68-year-old male with a 5-year history of compensatory hyper...

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Veröffentlicht in:	The Journal of dermatological treatment 2002, Vol.13 (2), p.91-93
Hauptverfasser:	Huh, CH, Han, KH, Seo, KI, Eun, HC
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - antagonists & inhibitors Aged Biological and medical sciences Botulinum Toxin Botulinum Toxins - therapeutic use Cholinergic Fibers - drug effects Cholinergic Fibers - metabolism Compensatory Hyperhidrosis Humans Hyperhidrosis - drug therapy Hyperhidrosis - surgery Male Medical sciences Pharmacology. Drug treatments Skin, nail, hair, dermoskeleton Sweat Glands - innervation Sympathectomy Thorax - innervation
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Zusammenfassung:	BACKGROUND : Compensatory hyperhidrosis is the commonest complication of sympathectomy, but there's no known effective treatment. METHODS : Botulinum toxin type A (a total dose of 300 MU, 1.0 MU/cm 2 ) was used successfully to treat a 68-year-old male with a 5-year history of compensatory hyperhidrosis of the anterior chest following thoracic sympathectomy for palmar hyperhidrosis. RESULTS : The hyperhidrosis resolved for 8 months without systemic side effects. CONCLUSION : Intracutaneous injection of botulinum toxin is a fast, safe, effective and well-accepted approach for treatment of compensatory hyperhidrosis.
ISSN:	0954-6634 1471-1753
DOI:	10.1080/095466302317584467