METASTASIZED ANGIOSARCOMA OF THE SPLEEN IN A 2-YEAR-OLD GIRL

Primary angiosarcoma of the spleen is rare and the prognosis is very poor. The authors present a 2-year-old girl with spontaneous rupture of splenic angiosarcoma. At diagnosis there were liver metastases. After splenectomy she received chemotherapy with ifosfamide, vincristine, and actinomycine D co...

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Veröffentlicht in:	Pediatric hematology and oncology 2005-07, Vol.22 (5), p.387-390
Hauptverfasser:	den Hoed, Irma D. M., Granzen, B., Aronson, Daniel C., Pauwels, Patrick, de Kraker, J., van Heurn, L. W. Ernest
Format:	Artikel
Sprache:	eng
Schlagworte:	angiosarcoma Antineoplastic Combined Chemotherapy Protocols - therapeutic use chemotherapy Child, Preschool Female Hemangiosarcoma - diagnosis Hemangiosarcoma - secondary Hemangiosarcoma - therapy Hepatectomy hepatic metastases Humans Liver Neoplasms - diagnosis Liver Neoplasms - secondary Liver Neoplasms - therapy Neoplasm Metastasis Prognosis Remission Induction spleen Splenic Neoplasms - diagnosis Splenic Neoplasms - pathology Splenic Neoplasms - therapy
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Zusammenfassung:	Primary angiosarcoma of the spleen is rare and the prognosis is very poor. The authors present a 2-year-old girl with spontaneous rupture of splenic angiosarcoma. At diagnosis there were liver metastases. After splenectomy she received chemotherapy with ifosfamide, vincristine, and actinomycine D combined with a partial liver resection. She remained in complete remission over 2 years from diagnosis.
ISSN:	0888-0018 1521-0669
DOI:	10.1080/08880010590964228