Disaccharide Nucleosides And Their Enzymatic And Chemical Incorporation Into Oligonucleotides

Disaccharide Nucleosides And Their Enzymatic And Chemical Incorporation Into Oligonucleotides

A high yield synthesis of different O-ribofuranosylnucleosides has been achieved. Kinetics of the acid-catalysed hydrolysis of disaccharide nucleosides has been studied. Chemical and enzymatic incorporation of 2′-O-ribofuranosyl-nucleoside residue into oligonucleotides was investigated.

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Veröffentlicht in:Nucleosides & nucleotides 1998-09, Vol.17 (9-11), p.1681-1684
Hauptverfasser: Efimtseva, Ekaterina V., Victorova, Lubov S., Rodionov, Andrei A., Ermolinsky, Boris S., Fomitcheva, Marina V., Tunitskaya, Vera L., Mikhailov, Sergey N., Oivanen, Mikko, Van Aerschot, Arthur, Herdewijn, Piet
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Sprache:eng
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Zusammenfassung:A high yield synthesis of different O-ribofuranosylnucleosides has been achieved. Kinetics of the acid-catalysed hydrolysis of disaccharide nucleosides has been studied. Chemical and enzymatic incorporation of 2′-O-ribofuranosyl-nucleoside residue into oligonucleotides was investigated.
ISSN:0732-8311
DOI:10.1080/07328319808004701