Ring Opening Reaction of Pyrazolo[3,4-c]Maleimide Nucleosides

Ring Opening Reaction of Pyrazolo[3,4-c]Maleimide Nucleosides

Synthesis of pyrazolo[3,4-c]maleimide nucleosides was attempted, but ring opening reaction of the maleimide part was observed during ammonolysis of sugar-protected pyrazolo[3,4-c]maleimide nucleosides. The isolated pyrazole nucleosides were characterized by NMR spectra and X-ray analysis.

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Veröffentlicht in:Nucleosides & nucleotides 1997-10, Vol.16 (10-11), p.2025-2033
Hauptverfasser: Kim, Sungjoong, Won, Wooyeon, Kang, Yonghan
Format: Artikel
Sprache:eng
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Zusammenfassung:Synthesis of pyrazolo[3,4-c]maleimide nucleosides was attempted, but ring opening reaction of the maleimide part was observed during ammonolysis of sugar-protected pyrazolo[3,4-c]maleimide nucleosides. The isolated pyrazole nucleosides were characterized by NMR spectra and X-ray analysis.
ISSN:0732-8311
DOI:10.1080/07328319708002553