Synthesis and liquid-crystalline behaviour of liposaccharide based comb polymers

In order to investigate the relationship between the liquid-crystalline state and the biological properties of polymers, we synthesized and studied liquid-crystalline comb polymers with a polyacrylamide main chain and three types of lipo-saccharidic side chains. These comb polymers were synthesized...

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Veröffentlicht in:Liquid crystals 1989-01, Vol.5 (6), p.1729-1735
Hauptverfasser: Gallot, Bernard, Marchin, Brigitte
Format: Artikel
Sprache:eng
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Zusammenfassung:In order to investigate the relationship between the liquid-crystalline state and the biological properties of polymers, we synthesized and studied liquid-crystalline comb polymers with a polyacrylamide main chain and three types of lipo-saccharidic side chains. These comb polymers were synthesized in four steps: first the polymerizable group was linked to the amino end of an α,ω-aliphatic amino acid; in the second step the ω-carboxylic acid function was activated in the form of an N-hydroxysuccinimidylester; in the third step the active ester was aminolysed by the amine function of the saccharide (N-methyl-D-glucamine, 2-amino-2-deoxy-β-D-glucose or 1-amino-1-deoxy-β-D-galactose) and a polymerizable liposaccharide was obtained; finally the liposaccharides were transformed into comb polymers by free-radical polymerization. Comb polymers exhibit mesophases in concentrated aqueous, ethanol or dimethylsulphoxide solution, and their mesomorphic character remains after the slow evaporation of the solvent. X-ray diffraction studies have shown that the mesophases have smectic or nematic ordering, depending upon the nature of the saccharidic residues of the liposaccharidic side chains.
ISSN:0267-8292
1366-5855
DOI:10.1080/02678298908045683