Microencapsulation by means of step-wise adsorption of polyelectrolytes

Step-wise adsorption of polyelectrolytes is used for the fabrication of microand nanocapsules with determined size, capsule wall composition and thickness. The capsule walls made of polyelectrolyte multilayers exclude high molecular weight compounds. Assembling of lipid layers onto these polyelectro...

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Veröffentlicht in:	Journal of microencapsulation 2000, Vol.17 (2), p.177-185
Hauptverfasser:	Sukhorukov, G B, Donath, E, Moya, S, Susha, A S, Voigt, A, Hartmann, J, Möhwald, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Drug Compounding - methods Electrolytes - chemistry Electrolytes - pharmacokinetics Fluorescence Lipid Metabolism Lipids - chemistry Magnetics Microscopy, Confocal Microscopy, Electron, Scanning Microspheres Permeability Phosphatidic Acids - chemistry Polyamines - chemistry Polyelectrolyte Nanoparticles Lipid Microcapsules Nanocapsules Polymers - chemistry Polymers - pharmacokinetics Polystyrenes - chemistry
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Beschreibung
Zusammenfassung:	Step-wise adsorption of polyelectrolytes is used for the fabrication of microand nanocapsules with determined size, capsule wall composition and thickness. The capsule walls made of polyelectrolyte multilayers exclude high molecular weight compounds. Assembling of lipid layers onto these polyelectrolyte capsules prevents the permeation of small dyes. Encapsulation of magnetite nanoparticles is demonstrated and the features of these novel capsules are discussed.
ISSN:	0265-2048 1464-5246
DOI:	10.1080/026520400288418