Synthesis of Thieno[b]quinolizidines and Hofmann Elimination on Methiodides Derivatives

Synthesis of Thieno[b]quinolizidines and Hofmann Elimination on Methiodides Derivatives

Thieno[b]quinolizidines were synthesized by reduction of thieno[b]quinolizidinones and the stereochemistry of their methiodide derivatives was studied. Hofmann degradation of the latter led to thienoazecines.

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Veröffentlicht in:Synthetic communications 1998-03, Vol.28 (6), p.949-956
Hauptverfasser: Berkes, Dusan, Netchitaïlo, Pierre, Morel, Jean, Decroix, Bernard
Format: Artikel
Sprache:eng
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Zusammenfassung:Thieno[b]quinolizidines were synthesized by reduction of thieno[b]quinolizidinones and the stereochemistry of their methiodide derivatives was studied. Hofmann degradation of the latter led to thienoazecines.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397919808003063