Synthesis and Reactivity of bis-Lactamic Compounds

Synthesis and Reactivity of bis-Lactamic Compounds

A preparation of bis-lactams is described from α-ketols and bis-cyanamides in the presence of sodium ethoxide at room temperature. One of these compounds leads to an unsaturated derivative by condensation with furfural, or to a saturated analogue via catalytic hydrogenation.

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Veröffentlicht in:Synthetic communications 1997-06, Vol.27 (11), p.1919-1925
Hauptverfasser: Alexandre, Christian, Melikian, Gaguik, Rouessac, Francis
Format: Artikel
Sprache:eng
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Zusammenfassung:A preparation of bis-lactams is described from α-ketols and bis-cyanamides in the presence of sodium ethoxide at room temperature. One of these compounds leads to an unsaturated derivative by condensation with furfural, or to a saturated analogue via catalytic hydrogenation.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397919708006793