The Efficient Synthesis of N4-Substituted 1-Methylcytosines

An improved procedure for the preparation of 4-chloro-1, 2-dihydro-1-methyl-2-oxopyrimidine is described. This compound appeared to be an excellent substrate for the synthesis of N 4 -substituted 1-methylcytosines.

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Veröffentlicht in:Synthetic communications 1991-01, Vol.21 (14), p.1489-1500
Hauptverfasser: Celewicz, Lech, Ciszewski, Krzysztof, Golankiewicz, Krzysztof
Format: Artikel
Sprache:eng
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Zusammenfassung:An improved procedure for the preparation of 4-chloro-1, 2-dihydro-1-methyl-2-oxopyrimidine is described. This compound appeared to be an excellent substrate for the synthesis of N 4 -substituted 1-methylcytosines.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397919108016423