Oxygen and 2,3 biphosphoglycerate (2,3-BPG) during haemodialysis

Eleven patients with chronic renal failure who were being treated with haemodialysis three times a week were monitored for a total of 34 haemodialysis sessions. Erythrocyte 2,3-biphosphoglycerate (2,3-BPG) concentration was analysed immediately before initiation of bicarbonate haemodialysis and 1 h...

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Veröffentlicht in:Scandinavian journal of clinical and laboratory investigation 1998, Vol.58 (6), p.459-468
1. Verfasser: A L Nielsen, E M Andersen, L G M Jørgensen, H Æ Jensen
Format: Artikel
Sprache:eng
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Zusammenfassung:Eleven patients with chronic renal failure who were being treated with haemodialysis three times a week were monitored for a total of 34 haemodialysis sessions. Erythrocyte 2,3-biphosphoglycerate (2,3-BPG) concentration was analysed immediately before initiation of bicarbonate haemodialysis and 1 h afterwards. The 2,3-BPG concentration was expressed relative to the haemoglobin tetramer (Hb4) concentration as the 2,3-BPG/Hb4 ratio and compared with blood gas analyses and biochemical variables important for characterizing uraemia. During the first hour of haemodialysis the 2,3-BPG/Hb4 ratio decreased (p
ISSN:0036-5513
1502-7686
DOI:10.1080/00365519850186256