Compound-Independent Calibration by Gas Chromatography-Atomic Emission Detection (GC-AED): Analysis of Molecules with 12 Carbon Atoms

This study was designed to demonstrate that Gas Chromatography-Atomic Emission Detection (GC-AED) can be used to set in a Compound-independent calibration (CIC) for quantifying organic compounds with various chemical functions using one reference compound. Experiments were carried out with thirteen organic molecules containing twelve atoms of carbon and different amount of hydrogen, oxygen or sulphur. The results obtained show that the GC-AED technique allows to quantify a molecule of known chemical structure using the elemental response of C or H and another different molecule as the standard of calibration.