Multidrug Resistance and Electromagnetic Fields

Multidrug Resistance and Electromagnetic Fields

The effect of low-frequency electromagnetic fields (EMFs) on the multidrug resistant cell line MCF7 dx was studied. In cultures containing 40 mg/ml doxorubicin, incorporation of H3-thymidine was inhibited by exposure to EMFs. The effect may have occurred via functional inhibition of P-glycoprotein.

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Veröffentlicht in:Electromagnetic biology and medicine 1990, Vol.9 (2), p.209-212
Hauptverfasser: Petrini, Mario, Mattii, Letizia, Sabbatini, Antoinetta, Carulli, Giovanni, Grassi, Bruno, Cadossi, Ruggero, Ronca, Giovanni, Conte, Angela
Format: Artikel
Sprache:eng
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Zusammenfassung:The effect of low-frequency electromagnetic fields (EMFs) on the multidrug resistant cell line MCF7 dx was studied. In cultures containing 40 mg/ml doxorubicin, incorporation of H3-thymidine was inhibited by exposure to EMFs. The effect may have occurred via functional inhibition of P-glycoprotein.
ISSN:1536-8378
0730-823X
1536-8386
DOI:10.3109/15368379009119809